{"id":"W1997516537","doi":"10.1016/j.immuni.2009.07.010","title":"Marked Induction of the Helix-Loop-Helix Protein Id3 Promotes the γδ T Cell Fate and Renders Their Functional Maturation Notch Independent","year":2009,"lang":"en","type":"article","venue":"Immunity","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":162,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institute of Allergy and Infectious Diseases; Sunnybrook Research Institute","keywords":"Biology; Thymocyte; Cell biology; Cell fate determination; T-cell receptor; T cell; Signal transduction; Notch signaling pathway; CD8; Progenitor cell; Lineage (genetic); Clonal deletion; Gene; Genetics; Stem cell; Transcription factor; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005186097,0.0001842729,0.0001656546,0.0000744039,0.0006199547,0.00003537421,0.0002028366,0.000234545,0.0004520362],"category_scores_gemma":[0.00009609612,0.0001075928,0.0001039082,0.0001832616,0.0001945648,0.0002365735,0.00008241362,0.0008103853,0.00005463804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005892843,"about_ca_system_score_gemma":0.00005657793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002467853,"about_ca_topic_score_gemma":0.00003251099,"domain_scores_codex":[0.9985453,0.0006514888,0.0003392158,0.0001917428,0.00007571932,0.0001965406],"domain_scores_gemma":[0.9990239,0.00007830184,0.000294284,0.000430841,0.0001613322,0.0000114147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005728989,0.0001676783,0.00009735251,0.00001406368,0.00005682519,9.904039e-8,0.0007844331,0.000007970603,0.9902732,0.000206767,0.001525872,0.006292889],"study_design_scores_gemma":[0.0008764933,0.0002428024,0.111909,0.00004913564,0.00003518134,0.00005698104,0.002113218,0.00002523741,0.8762214,0.0004045838,0.007924843,0.0001411216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992404,0.0007396339,0.0001507465,0.001867571,0.001935764,0.0006493197,0.000005719291,0.00004831305,0.002198945],"genre_scores_gemma":[0.9909032,0.00005207417,0.00001020052,0.000231537,0.00003669602,0.0000259299,0.00007839924,0.000009738561,0.008652246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1140518,"threshold_uncertainty_score":0.494948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01481206070051147,"score_gpt":0.2052533557174883,"score_spread":0.1904412950169769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}