{"id":"W1997525701","doi":"10.1074/jbc.m605316200","title":"Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"Institut National de la Santé et de la Recherche Médicale","keywords":"Adenovirus infection; Virology; Mastadenovirus; Domain (mathematical analysis); Biology; Adenoviridae; Computational biology; Genetics; Gene; Recombinant DNA; Virus; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001520468,0.0003134174,0.000212372,0.0002024332,0.0002213001,0.0001753298,0.0003033289,0.0002460824,0.001214308],"category_scores_gemma":[0.0002151512,0.0001999385,0.0002915762,0.0002065621,0.0001969,0.0001679864,0.0001471006,0.0003020946,0.000226904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001077938,"about_ca_system_score_gemma":0.0003054765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0087326,"about_ca_topic_score_gemma":0.008577222,"domain_scores_codex":[0.9998926,0.00001533554,0.000006214808,0.00002160922,0.00004076433,0.00002347463],"domain_scores_gemma":[0.9999075,0.00002214754,0.00001826727,0.000007623302,0.00001501373,0.00002941839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003247361,0.00008347313,0.003051247,0.00009724845,0.00003633348,0.0002861501,0.0001494429,0.000915731,0.9924458,0.0005292101,0.0001701843,0.001910473],"study_design_scores_gemma":[0.00008370118,0.0005049102,0.07549071,0.00002563403,0.0001055366,0.002214682,0.0004427539,0.0150805,0.8966803,0.0003532407,0.008973714,0.00004443306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987293,0.0003873616,0.0003745565,0.00002781783,0.000004060149,0.000005695916,0.0001201148,0.000009190555,0.0003419041],"genre_scores_gemma":[0.996839,0.0002289733,0.001240475,0.00003564552,0.000002345177,0.000007349489,0.0009213306,0.000009728211,0.0007150336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0087326,"threshold_uncertainty_score":0.01736349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02287464026980064,"score_gpt":0.2963631317306971,"score_spread":0.2734884914608964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}