{"id":"W1997546231","doi":"10.1038/sj.gt.3302968","title":"Nacystelyn enhances adenoviral vector-mediated gene delivery to mouse airways","year":2007,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Foundation Fighting Blindness; Cystic Fibrosis Foundation","keywords":"Genetic enhancement; Gene delivery; Viral vector; Adenoviridae; Cystic fibrosis; Vector (molecular biology); Nebulizer; Mucociliary clearance; Immunology; Biology; Medicine; Pharmacology; Virology; Gene; Recombinant DNA; Lung; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000284622,0.0002616289,0.0002031784,0.00009959059,0.0001002374,0.00003231447,0.0004005693,0.0001958178,0.00009178869],"category_scores_gemma":[0.00002113296,0.0002424396,0.0001325223,0.0001675893,0.00005369583,0.000007733126,0.00008975162,0.00009573791,0.00029108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002694028,"about_ca_system_score_gemma":0.00006612424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008450227,"about_ca_topic_score_gemma":0.0001322319,"domain_scores_codex":[0.9984435,0.00004486612,0.0003037192,0.0004926788,0.0002062028,0.000509048],"domain_scores_gemma":[0.999088,0.00001653886,0.00007760632,0.00048146,0.0001458769,0.0001905504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006955852,0.0000713013,0.0004127846,0.000002676532,0.00008236519,0.00001248094,0.0002021988,0.00003644068,0.9857319,0.000002753884,0.002453308,0.01029621],"study_design_scores_gemma":[0.0006220278,0.001108225,0.002683715,0.000005291188,0.000005416102,0.00001281661,0.00008374194,0.000004979453,0.9630517,0.000007450151,0.03209859,0.0003160406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929509,0.00350929,0.002320512,0.000104853,0.0003727068,0.0002579424,0.00004372077,0.00004462415,0.0003954303],"genre_scores_gemma":[0.9921197,0.002238882,0.0008004449,0.002232819,0.0007741954,0.00002331502,0.000201915,0.0000426905,0.001566089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02964528,"threshold_uncertainty_score":0.9886401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01362357695003178,"score_gpt":0.2531554162758518,"score_spread":0.23953183932582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}