{"id":"W1997546231","doi":"10.1038/sj.gt.3302968","title":"Nacystelyn enhances adenoviral vector-mediated gene delivery to mouse airways","year":2007,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Foundation Fighting Blindness; Cystic Fibrosis Foundation","keywords":"Genetic enhancement; Gene delivery; Viral vector; Adenoviridae; Cystic fibrosis; Vector (molecular biology); Nebulizer; Mucociliary clearance; Immunology; Biology; Medicine; Pharmacology; Virology; Gene; Recombinant DNA; Lung; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000601391,0.0005446154,0.0006181314,0.0006926252,0.0003407654,0.0006548202,0.0005892029,0.0006418466,0.001880064],"category_scores_gemma":[0.0003169949,0.0003323653,0.0004417895,0.0002864906,0.0006683694,0.0006851285,0.0003564169,0.001242334,0.0005836747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007815057,"about_ca_system_score_gemma":0.0006412336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001552302,"about_ca_topic_score_gemma":0.003119584,"domain_scores_codex":[0.9992995,0.0001311703,0.00007416706,0.0001286917,0.0002150564,0.0001513141],"domain_scores_gemma":[0.9995164,0.000131683,0.0001214017,0.00005688113,0.00004872135,0.0001249401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001532605,0.00002473876,0.00005145239,0.00002908247,0.000002990208,0.0000303451,0.00001349218,0.00004620285,0.9989349,0.0001590335,0.00002084423,0.0005337184],"study_design_scores_gemma":[0.00001091793,0.0001305182,0.000398875,0.000002726773,0.000008190885,0.00006799318,0.000007216652,0.0003224339,0.9982064,0.00001742376,0.0008251754,0.000002085205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771504,0.00481484,0.01031244,0.0003746325,0.0001845125,0.0002226831,0.0008356108,0.000529715,0.005575163],"genre_scores_gemma":[0.9811563,0.001663214,0.007649345,0.00006682836,0.00005208874,0.0000976215,0.0005895746,0.0001018106,0.008623287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001880064,"threshold_uncertainty_score":0.006289423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01362357695003178,"score_gpt":0.2531554162758518,"score_spread":0.23953183932582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}