{"id":"W1997604908","doi":"10.1016/j.neuron.2010.02.008","title":"Layers upon Layers: MHC Class I Acts in the Retina to Influence Thalamic Segregation","year":2010,"lang":"en","type":"letter","venue":"Neuron","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Neuroscience; Retina; Major histocompatibility complex; Biology; Synaptic plasticity; Structural plasticity; Neuroplasticity; MHC class I; Neuron; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002200387,0.0002875698,0.0001644193,0.0000994491,0.00006201786,0.00008322507,0.0006104765,0.0009537631,0.00001177268],"category_scores_gemma":[0.0001997456,0.0002297344,0.00007963098,0.0001778479,0.00004326275,0.0000101755,0.0001156834,0.00141487,0.00006981008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001736911,"about_ca_system_score_gemma":0.00009361886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003810708,"about_ca_topic_score_gemma":0.0001933127,"domain_scores_codex":[0.9983757,0.0001605217,0.0002285719,0.0005345729,0.0003284875,0.0003721071],"domain_scores_gemma":[0.9992378,0.00003781806,0.0001191928,0.0005143105,0.00005455739,0.00003628881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001123097,0.00003103656,0.002684266,0.00009564135,0.000016261,0.0001286768,0.0003212802,0.0001333911,0.2346703,0.00004217388,0.7605302,0.001234509],"study_design_scores_gemma":[0.0002261283,0.0001836372,0.01179766,0.00003923789,0.00001183424,0.00001724948,0.00003325759,0.000007534541,0.006424643,0.0001011465,0.9808418,0.0003159409],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7790183,0.00004832274,0.00001379151,0.2148682,0.000331679,0.0004373149,0.000007203374,0.00001373304,0.005261482],"genre_scores_gemma":[0.5269817,0.0001285688,0.0001057831,0.4706471,0.0005731185,0.00007087367,0.0005009579,0.00005041106,0.0009414571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.255779,"threshold_uncertainty_score":0.9368296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008306389414903113,"score_gpt":0.2378659914502133,"score_spread":0.2295596020353102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}