{"id":"W1997604908","doi":"10.1016/j.neuron.2010.02.008","title":"Layers upon Layers: MHC Class I Acts in the Retina to Influence Thalamic Segregation","year":2010,"lang":"en","type":"letter","venue":"Neuron","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Neuroscience; Retina; Major histocompatibility complex; Biology; Synaptic plasticity; Structural plasticity; Neuroplasticity; MHC class I; Neuron; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003270675,0.0003688506,0.0003835701,0.0001537951,0.0005056934,0.0008531742,0.0005788609,0.004079118,0.006288877],"category_scores_gemma":[0.00125648,0.0001970679,0.0002060037,0.0001181184,0.0009744225,0.0008452052,0.000284349,0.004192412,0.00217122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007690888,"about_ca_system_score_gemma":0.0002470512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008860425,"about_ca_topic_score_gemma":0.001482838,"domain_scores_codex":[0.9998875,0.00002510093,0.00001127077,0.00002362559,0.00002626594,0.00002622654],"domain_scores_gemma":[0.9996274,0.000198011,0.00003027118,0.00003348268,0.00004812602,0.00006270726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005333768,0.0001796423,0.00473147,0.0006126828,0.0001311315,0.03286724,0.0004195927,0.001346867,0.1291066,0.02536411,0.7041985,0.09570846],"study_design_scores_gemma":[0.001188332,0.0007149252,0.01498312,0.0001922409,0.0001686758,0.02842969,0.0009394015,0.008619686,0.08873411,0.05287236,0.8029908,0.0001667018],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.05858437,0.0126198,0.004395802,0.8353167,0.05556181,0.00005654779,0.0004435728,0.0004518338,0.03256958],"genre_scores_gemma":[0.5054054,0.01770388,0.00359075,0.2522127,0.09502342,0.000128562,0.0002669705,0.0001718617,0.1254964],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.006288877,"threshold_uncertainty_score":0.02103841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008306389414903113,"score_gpt":0.2378659914502133,"score_spread":0.2295596020353102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}