{"id":"W1997617537","doi":"10.1371/journal.pone.0089284","title":"Positive Regulation of TRAF6-Dependent Innate Immune Responses by Protein Phosphatase PP1-γ","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Cancer Institute; National Institute of General Medical Sciences; U.S. Public Health Service; National Institute on Aging","keywords":"Innate immune system; Signal transducing adaptor protein; Ubiquitin ligase; Cell biology; Biology; Proinflammatory cytokine; Immune system; Phosphatase; Ubiquitin; Protein phosphatase 1; Protein phosphatase 2; Regulator; Protein subunit; Signal transduction; Phosphorylation; Immunology; Inflammation; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004046474,0.0001795381,0.0003910336,0.0001240194,0.0001095163,0.00001126062,0.000210407,0.0002016667,0.0007469599],"category_scores_gemma":[0.000417827,0.0001667527,0.00007649518,0.00009817279,0.0002062508,0.0001134743,0.0000739062,0.0002328669,0.0004146676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003994981,"about_ca_system_score_gemma":0.0000398787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001082521,"about_ca_topic_score_gemma":0.000003720223,"domain_scores_codex":[0.998298,0.000660096,0.0004309817,0.0002476377,0.00008201607,0.0002812989],"domain_scores_gemma":[0.9990286,0.0002063305,0.000219734,0.0003689022,0.0001573121,0.00001909793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004629543,0.001203121,0.00008202152,0.00004317838,0.0003829119,8.838784e-7,0.0002842989,3.016924e-7,0.9902362,0.001231382,0.0004232969,0.001482808],"study_design_scores_gemma":[0.001481384,0.0009954463,0.004331617,0.0002902627,0.00008430905,0.000006294253,0.00006694486,0.000008990764,0.9914551,0.00009997011,0.001001186,0.0001785087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938625,0.003963268,0.0001154434,0.0004146557,0.00007262252,0.0004951219,0.0002077513,0.0000671283,0.0008015689],"genre_scores_gemma":[0.9790544,0.00005147788,0.0001202018,0.00008028698,0.0000117117,0.00004929431,0.000290213,0.0000235857,0.02031882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01951725,"threshold_uncertainty_score":0.8178687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01451901653621741,"score_gpt":0.215214702943094,"score_spread":0.2006956864068766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}