{"id":"W1997675522","doi":"10.1016/s0167-4889(01)00170-7","title":"Inhibition of somatostatin receptor 5-signaling by mammalian regulators of G-protein signaling (RGS) in yeast","year":2002,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"G protein-coupled receptor; G protein; Somatostatin; Cell biology; Signal transduction; Somatostatin receptor; Receptor; Somatostatin receptor 3; Biology; Gi alpha subunit; Somatostatin receptor 2; Regulator of G protein signaling; Gs alpha subunit; HEK 293 cells; GTPase-activating protein; Biochemistry; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001117697,0.0003097063,0.000410149,0.0005165066,0.00006953849,0.00003800297,0.0003551228,0.0003219568,0.00009365207],"category_scores_gemma":[0.0001409273,0.0003415944,0.0002040058,0.00099457,0.0003175577,0.00002131095,0.0002150441,0.0004121212,0.00001328024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006437472,"about_ca_system_score_gemma":0.0001198774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001155728,"about_ca_topic_score_gemma":0.000007963616,"domain_scores_codex":[0.9962706,0.0007700791,0.0008026473,0.0007191173,0.0008023301,0.0006352299],"domain_scores_gemma":[0.9986551,0.00004116746,0.0003088616,0.000580192,0.0002543379,0.0001603337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001710566,0.0004669691,0.00002085313,0.0002247081,0.00002290623,0.00001318549,0.0002591172,0.0001304971,0.9979393,0.0001515858,0.0001966539,0.0004031345],"study_design_scores_gemma":[0.001160557,0.0003302491,0.0000580864,0.0003484429,0.000007765293,0.000001277763,0.0002348413,0.0004257,0.9967413,0.0001799133,0.0001916071,0.0003202693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971648,0.0008845477,0.0002380278,0.0002684403,0.00002235855,0.0007575798,0.00008533962,0.00001230572,0.0005665347],"genre_scores_gemma":[0.997743,0.0001021016,0.001505629,0.00004107944,0.0000454784,0.00007037153,0.000256145,0.00007072231,0.0001655155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002384511,"threshold_uncertainty_score":0.9999036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02181083181386198,"score_gpt":0.2742812291988959,"score_spread":0.252470397385034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}