{"id":"W1997689151","doi":"10.1016/s0969-2126(01)00702-x","title":"Phosphoserine-Dependent Regulation of Protein-Protein Interactions in the Smad Pathway","year":2002,"lang":"en","type":"article","venue":"Structure","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"SMAD; Phosphoserine; Cell biology; Signal transduction; Phosphorylation; Transmembrane protein; Serine; Protein kinase A; Chemistry; Biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006034533,0.0000976767,0.00007458466,0.00002807373,0.00004028137,0.00001300171,0.0001840318,0.00006051294,0.0002667447],"category_scores_gemma":[0.00007568404,0.00007305269,0.00004610776,0.00008040119,0.00003825287,0.000004012924,0.00003788418,0.0001001915,0.000003468381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001011946,"about_ca_system_score_gemma":0.00001742741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002350088,"about_ca_topic_score_gemma":0.0001086203,"domain_scores_codex":[0.9993488,0.00007136761,0.0001636876,0.0001753729,0.0001299563,0.0001107783],"domain_scores_gemma":[0.9995188,0.000006226423,0.00008532073,0.0003269181,0.00004119888,0.0000215577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003984028,0.0000362674,0.0005398307,0.00002043106,0.00001182071,0.000001590143,0.0001673393,0.0001827073,0.9960862,0.0001466332,0.000137393,0.002629927],"study_design_scores_gemma":[0.000247018,0.00005459749,0.0118896,0.00003012594,0.000004945657,0.000007133533,0.00008185032,0.00004132028,0.9793714,0.0006260383,0.007550305,0.00009562146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998407,0.0005235807,0.00009405478,0.00009999872,0.00005987586,0.0003160363,0.00003844337,0.000007634207,0.0004533838],"genre_scores_gemma":[0.9988103,0.000002244413,0.0002880643,0.00004684545,0.0001037007,0.00003283568,0.00005168483,0.00001164807,0.0006526642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01671478,"threshold_uncertainty_score":0.2979002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01043073105809027,"score_gpt":0.2322590478806025,"score_spread":0.2218283168225123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}