{"id":"W1997710934","doi":"10.1515/bc.2008.118","title":"Substrate specificity determination of mouse implantation serine proteinase and human kallikrein-related peptidase 6 by phage display","year":2008,"lang":"en","type":"article","venue":"Biological Chemistry","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital; University of Calgary","funders":"","keywords":"Biopanning; Kallikrein; Trypsin; Serine; Biochemistry; Phage display; Serine protease; Peptide library; Enzyme; Chymotrypsin; Chemistry; Molecular biology; Proteases; Tryptophan; Peptide; Proteinase 3; Protease; Biology; Amino acid; Peptide sequence; Gene; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002512613,0.000318666,0.0003321496,0.0001964477,0.00008309888,0.0002963668,0.000194253,0.0002539171,0.0005966625],"category_scores_gemma":[0.00037498,0.0001503948,0.0001773703,0.0001945809,0.00009124837,0.0001505493,0.0002037513,0.0003285667,0.0003000357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001222923,"about_ca_system_score_gemma":0.00007946435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001267113,"about_ca_topic_score_gemma":0.0001824402,"domain_scores_codex":[0.9997258,0.0000681825,0.00002056736,0.00004489259,0.00009205776,0.00004853426],"domain_scores_gemma":[0.9998363,0.0000552063,0.00002303273,0.00001783832,0.00003434591,0.00003322139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000384183,0.000009195147,0.0001431621,0.00001111094,0.000002098145,0.00002312965,0.000006337228,0.00005391166,0.9990005,0.00001720529,0.00000635356,0.0006885024],"study_design_scores_gemma":[0.000004308521,0.000148608,0.001388821,0.000001493366,0.000007525194,0.0001989841,0.000008281243,0.0007226529,0.997003,0.0000136129,0.000499928,0.000002852104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907684,0.0005832547,0.007481946,0.00002854286,0.000007298207,0.00003687986,0.0001835057,0.00004550469,0.0008646571],"genre_scores_gemma":[0.9864825,0.0004612262,0.01058416,0.00002876442,0.000005112151,0.00003140293,0.0007737537,0.0000258395,0.00160731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005966625,"threshold_uncertainty_score":0.00199604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02484655444834223,"score_gpt":0.2611111880728771,"score_spread":0.2362646336245349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}