{"id":"W1997718533","doi":"10.1074/jbc.m109.061622","title":"GREBP, a cGMP-response Element-binding Protein Repressing the Transcription of Natriuretic Peptide Receptor 1 (NPR1/GCA)","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Biology; NPR1; Chromatin immunoprecipitation; Molecular biology; Luciferase; NPR2; Atrial natriuretic peptide; Transcription (linguistics); SOX4; Gene expression; Promoter; Gene; Natriuretic peptide; Biochemistry; Transfection; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000159613,0.0007295489,0.0005315583,0.0003364065,0.0002384403,0.000246672,0.0004122104,0.0005207731,0.001869014],"category_scores_gemma":[0.0001935702,0.0001839685,0.0004671831,0.0002512028,0.0004307839,0.0001637457,0.0003154537,0.001003749,0.001508482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000334599,"about_ca_system_score_gemma":0.0003040214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009414038,"about_ca_topic_score_gemma":0.001083006,"domain_scores_codex":[0.9997453,0.00002860043,0.00001009785,0.0001015236,0.00007315449,0.00004128135],"domain_scores_gemma":[0.9998772,0.0000215857,0.00003492419,0.00001336561,0.00001508101,0.00003772393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006282614,0.00002062804,0.0001530762,0.00004671478,0.00000386198,0.00006536867,0.00001290215,0.00003765628,0.9978861,0.00007080391,0.00008410073,0.001556094],"study_design_scores_gemma":[0.00004433039,0.0002953679,0.01401163,0.00002108687,0.00003071204,0.001425142,0.00004746057,0.001401873,0.9717869,0.000170515,0.01075058,0.00001444364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9541654,0.007869237,0.02843187,0.0007709124,0.0003105567,0.0001652623,0.003714506,0.001138819,0.003433555],"genre_scores_gemma":[0.9473596,0.003380457,0.02611575,0.0004167949,0.00008798955,0.0001548221,0.01032612,0.0001998911,0.01195847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001869014,"threshold_uncertainty_score":0.006252527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03493998894192433,"score_gpt":0.267446999671388,"score_spread":0.2325070107294637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}