{"id":"W1997720154","doi":"10.3791/52345","title":"Rapid Identification of Chemical Genetic Interactions in <em>Saccharomyces cerevisiae</em>","year":2015,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute","keywords":"Saccharomyces cerevisiae; Mutant; Gene; Biology; Computational biology; DNA microarray; Eukaryote; RNA; Genetic screen; Genetics; Yeast; Mode of action; DNA; Gene expression; Genome; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005798404,0.000635839,0.0004993187,0.0009377961,0.0002693874,0.0005558091,0.0004130737,0.0003037019,0.002696937],"category_scores_gemma":[0.0004193444,0.0004085999,0.0004408205,0.0006096241,0.0002655739,0.0002820144,0.0005320804,0.0007797223,0.002005589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004902303,"about_ca_system_score_gemma":0.0003932184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001766308,"about_ca_topic_score_gemma":0.005249523,"domain_scores_codex":[0.9995089,0.0000568313,0.00006168944,0.00009248185,0.0002361285,0.00004390557],"domain_scores_gemma":[0.999625,0.000114507,0.00007507192,0.00007793553,0.00007336435,0.00003411564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002567705,0.00001914735,0.0001790526,0.00003008179,0.000005916003,0.00003312678,0.000008946274,0.00005088741,0.9960158,0.00009856978,0.0001711747,0.003361555],"study_design_scores_gemma":[0.000005815903,0.00005731394,0.001933141,0.000005900706,0.00001312738,0.00008840628,0.00001941549,0.0006602726,0.992964,0.00004583716,0.004199606,0.000007026769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.710223,0.002631918,0.2474281,0.000731217,0.0002127871,0.0007801849,0.02090308,0.005802567,0.01128711],"genre_scores_gemma":[0.6904224,0.003354849,0.2647918,0.0003911224,0.00003197,0.000842468,0.02272288,0.001390577,0.01605202],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.002696937,"threshold_uncertainty_score":0.009022117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04397005515351968,"score_gpt":0.4089806637685912,"score_spread":0.3650106086150715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}