{"id":"W1997720154","doi":"10.3791/52345","title":"Rapid Identification of Chemical Genetic Interactions in &lt;em&gt;Saccharomyces cerevisiae&lt;/em&gt;","year":2015,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute","keywords":"Saccharomyces cerevisiae; Mutant; Gene; Biology; Computational biology; DNA microarray; Eukaryote; RNA; Genetic screen; Genetics; Yeast; Mode of action; DNA; Gene expression; Genome; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005254595,0.000175889,0.0003279635,0.0002195776,0.00002638509,0.00005186187,0.0003924446,0.0001107182,0.00009140863],"category_scores_gemma":[0.0002415573,0.0001590708,0.0001737075,0.0002060043,0.00006709017,0.00001957278,0.0001531944,0.0001663511,0.00001930297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006750319,"about_ca_system_score_gemma":0.000174771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005440224,"about_ca_topic_score_gemma":0.000003152748,"domain_scores_codex":[0.9978129,0.0001862202,0.0009226286,0.0002441471,0.0005760831,0.0002580504],"domain_scores_gemma":[0.9984963,0.00001987897,0.0004898573,0.0002831596,0.0004858549,0.00022495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005146051,0.0004560975,0.0005394744,0.00002368333,0.00009751877,0.000008691632,0.0006431833,0.00002988052,0.993008,0.00001104412,0.002196456,0.002471435],"study_design_scores_gemma":[0.001979797,0.0004054258,0.0009913918,0.00006673963,0.00002058158,0.00006439078,0.0005157646,0.0001918145,0.9873415,0.00005852698,0.008212997,0.00015109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924237,0.006348896,0.0003733035,0.00006027199,0.000358461,0.0001638203,0.00001004424,0.000003210096,0.0002582789],"genre_scores_gemma":[0.9970425,0.0006045283,0.001685818,0.00003648263,0.0002891312,0.00001520725,0.00002457457,0.00002576929,0.0002759826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00601654,"threshold_uncertainty_score":0.6486719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04397005515351968,"score_gpt":0.4089806637685912,"score_spread":0.3650106086150715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}