{"id":"W1997739317","doi":"10.1371/journal.pone.0117304","title":"Ubiquitin Specific Protease 21 Is Dispensable for Normal Development, Hematopoiesis and Lymphocyte Differentiation","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften; Deutsche Forschungsgemeinschaft; Wellcome Trust; McGill University","keywords":"Biology; Knockout mouse; Haematopoiesis; Stem cell; Cell biology; Lymphopoiesis; GATA3; Transcription factor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001827172,0.0004622091,0.0003596201,0.0005596728,0.000227559,0.0005349047,0.0004138004,0.0005010811,0.002852132],"category_scores_gemma":[0.0002417866,0.0002610559,0.0003151222,0.0002800486,0.0003447561,0.0002631018,0.0004299482,0.0004434906,0.001015758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003034212,"about_ca_system_score_gemma":0.0002552151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004555792,"about_ca_topic_score_gemma":0.0005680448,"domain_scores_codex":[0.9996536,0.00004925435,0.00005561002,0.00006999294,0.0001075167,0.00006408773],"domain_scores_gemma":[0.9994369,0.00007959196,0.0001712927,0.00007765293,0.0000316578,0.0002027686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000173455,0.0000211013,0.0003905459,0.00003204549,0.000008126351,0.0003720671,0.00001357341,0.0000521449,0.9970379,0.0002767358,0.00007229246,0.001550172],"study_design_scores_gemma":[0.00005010588,0.0003313984,0.01800618,0.00002320126,0.00004952208,0.003766723,0.00006986564,0.00145003,0.9604485,0.0002611451,0.01552183,0.00002136041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883157,0.003226815,0.003578674,0.0001278797,0.00004186172,0.00002756346,0.001737128,0.0002157288,0.002728711],"genre_scores_gemma":[0.9883073,0.001502429,0.001868407,0.00005578065,0.00001864999,0.00003415179,0.002115938,0.0001038417,0.005993468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002852132,"threshold_uncertainty_score":0.009541392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06455580158495715,"score_gpt":0.2354023894789231,"score_spread":0.170846587893966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}