{"id":"W1997807500","doi":"10.1186/1471-2199-9-61","title":"Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1","year":2008,"lang":"en","type":"article","venue":"BMC Molecular Biology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Chang Gung University; Chang Gung Medical Foundation; Academia Sinica; National Science Council","keywords":"Corepressor; Heterochromatin; Biology; Cell biology; Chromatin immunoprecipitation; Chromatin; Heterochromatin protein 1; Promoter; Phosphorylation; Transcription factor; Regulation of gene expression; Gene expression; Repressor; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008755516,0.0003368277,0.0001477884,0.0001884139,0.0001815548,0.0002557159,0.0001701791,0.0001400496,0.003375656],"category_scores_gemma":[0.0001173543,0.0001395211,0.0002341148,0.0001060708,0.0001940643,0.0001423211,0.0001711686,0.0002826327,0.0006826105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003108561,"about_ca_system_score_gemma":0.0001675608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005038727,"about_ca_topic_score_gemma":0.0006227315,"domain_scores_codex":[0.9999423,0.000007342583,0.000002607484,0.00001371984,0.000009695853,0.00002441048],"domain_scores_gemma":[0.999918,0.000008211113,0.00003263096,0.000004734323,0.000005783623,0.00003055737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009135836,0.00008728444,0.001390681,0.00007021265,0.00001371433,0.0001122623,0.00003119524,0.0001310643,0.9947382,0.0001983305,0.0001537005,0.002159748],"study_design_scores_gemma":[0.0001019454,0.0003747516,0.0607348,0.00002972794,0.00003535989,0.0006035726,0.0001048559,0.003881019,0.9315488,0.0002435773,0.002327851,0.00001383372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973526,0.0009822631,0.0004837186,0.00004547247,0.00001786537,0.000005940989,0.0001381535,0.00003075413,0.0009433143],"genre_scores_gemma":[0.9979953,0.0004382224,0.0003178719,0.0000223603,0.000007677794,0.00001314922,0.0002328415,0.00001274815,0.0009598508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003375656,"threshold_uncertainty_score":0.0112927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01405017001227524,"score_gpt":0.2456752530863969,"score_spread":0.2316250830741216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}