{"id":"W1997833227","doi":"10.1158/1538-7445.am10-2559","title":"Abstract 2559: Development of carboplatin, docetaxel and combined carboplatin/docetaxel resistant ovarian cancer cell lines","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Sudbury Regional Hospital; University of Sudbury; Laurentian University","funders":"","keywords":"Carboplatin; Docetaxel; Ovarian cancer; Drug resistance; Chemotherapy; Clonogenic assay; Medicine; Pharmacology; Paclitaxel; IC50; Cancer research; Cell culture; Cancer; Oncology; Internal medicine; Biology; Cisplatin; Microbiology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003725363,0.0002725004,0.0004039599,0.0003378525,0.0002274991,0.0004526845,0.0004587694,0.0004031951,0.002417941],"category_scores_gemma":[0.0002847296,0.0002196428,0.0003771718,0.0005738838,0.0001477294,0.0001732178,0.0002419713,0.0008139008,0.001535736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003230648,"about_ca_system_score_gemma":0.0003672825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002037009,"about_ca_topic_score_gemma":0.003240718,"domain_scores_codex":[0.9996237,0.00004305498,0.0000734421,0.00006722928,0.0001512342,0.00004140343],"domain_scores_gemma":[0.9997731,0.00003455821,0.00002275572,0.00005428946,0.00008009777,0.00003518299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002638809,0.0004539923,0.001316384,0.0001504771,0.00002744504,0.0003503015,0.0001490743,0.00067522,0.9839787,0.0007769453,0.002678912,0.009178649],"study_design_scores_gemma":[0.0002180144,0.001669626,0.00966837,0.00003569409,0.0000788686,0.00167495,0.0001363938,0.005671442,0.933201,0.0001444945,0.04747478,0.00002635871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9426633,0.003867063,0.01924535,0.0008067656,0.0004103872,0.001507102,0.01588945,0.0004318698,0.01517876],"genre_scores_gemma":[0.8891237,0.00361755,0.03766402,0.0004659834,0.00005903648,0.001423401,0.03507348,0.0001863401,0.03238655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002417941,"threshold_uncertainty_score":0.008088827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02646286224492996,"score_gpt":0.3761022979649158,"score_spread":0.3496394357199859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}