{"id":"W1997880464","doi":"10.1095/biolreprod.102.013045","title":"Identification of Novel Isoforms of Activin Receptor-Like Kinase 7 (ALK7) Generated by Alternative Splicing and Expression of ALK7 and Its Ligand, Nodal, in Human Placenta1","year":2003,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of British Columbia; University of Ottawa; York University","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Biology; Alternative splicing; Exon; Gene isoform; ACVR2B; Molecular biology; Genetics; Gene; Receptor; TGF beta signaling pathway","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003292631,0.00009600673,0.0001920352,0.00007940639,0.00002776375,0.000001783074,0.00005828915,0.000123339,0.000002781893],"category_scores_gemma":[0.0002387054,0.00009041074,0.00002403427,0.00007827266,0.0001405047,0.00001121656,0.0000378019,0.00004228299,6.613988e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001019995,"about_ca_system_score_gemma":0.00002350072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006287931,"about_ca_topic_score_gemma":0.000007340526,"domain_scores_codex":[0.9990085,0.00007442524,0.0003882597,0.0003872145,0.00005568844,0.00008595076],"domain_scores_gemma":[0.9991228,0.00001149609,0.0004815103,0.0002274127,0.0001347818,0.00002201914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001502536,0.0002216667,0.009464168,0.00008608955,0.00002428175,4.13047e-8,0.000118274,0.00006894368,0.9891384,0.00002505095,0.00005483239,0.0006480016],"study_design_scores_gemma":[0.000649426,0.0002257457,0.0023926,0.00005417859,0.00001104414,0.000002692468,0.0001111627,0.00002470129,0.9962352,0.00001978288,0.0001969627,0.00007648353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955278,0.003745036,0.0003762891,0.00001276952,0.0001003866,0.0001838325,0.00004510126,0.000002939964,0.00000583539],"genre_scores_gemma":[0.9990836,0.0004232264,0.0002614884,0.000002179186,0.00003063575,0.000008267115,0.0001243966,0.000008503743,0.00005775346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007096824,"threshold_uncertainty_score":0.3686843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01423189671524374,"score_gpt":0.2742250596973351,"score_spread":0.2599931629820914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}