{"id":"W1997880464","doi":"10.1095/biolreprod.102.013045","title":"Identification of Novel Isoforms of Activin Receptor-Like Kinase 7 (ALK7) Generated by Alternative Splicing and Expression of ALK7 and Its Ligand, Nodal, in Human Placenta1","year":2003,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of British Columbia; University of Ottawa; York University","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Biology; Alternative splicing; Exon; Gene isoform; ACVR2B; Molecular biology; Genetics; Gene; Receptor; TGF beta signaling pathway","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001815903,0.0003295389,0.0002303327,0.0003969699,0.000161913,0.0003961463,0.0002389038,0.0003881544,0.0006583316],"category_scores_gemma":[0.0003736351,0.0003845321,0.0003675354,0.0001853317,0.0003609525,0.0001961991,0.0002983621,0.0003536231,0.0003879882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002122967,"about_ca_system_score_gemma":0.0002552704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002001632,"about_ca_topic_score_gemma":0.0002716846,"domain_scores_codex":[0.9998482,0.00001939792,0.00001573147,0.00003492541,0.00005746859,0.00002420768],"domain_scores_gemma":[0.9997521,0.0000649141,0.00008002875,0.00002667448,0.00003206419,0.00004430073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002931035,0.00002281137,0.003693291,0.00007223056,0.00002254486,0.001596713,0.00008282642,0.0001340089,0.9901177,0.0002775853,0.00008261483,0.003604698],"study_design_scores_gemma":[0.000278488,0.00160453,0.1122943,0.0000645514,0.0004409624,0.04329265,0.0004199745,0.006936813,0.8158359,0.001325874,0.0174421,0.00006399625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930891,0.002607114,0.003402425,0.00009851211,0.00003477218,0.00003320365,0.0002964875,0.0000298551,0.0004083735],"genre_scores_gemma":[0.9898751,0.001693464,0.00535178,0.00008623054,0.00006187866,0.00005750957,0.001817886,0.00002443732,0.001031706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006583316,"threshold_uncertainty_score":0.002202332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01423189671524374,"score_gpt":0.2742250596973351,"score_spread":0.2599931629820914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}