{"id":"W1997882620","doi":"10.1074/jbc.m802492200","title":"Separate cis-trans Pathways Post-transcriptionally Regulate Murine CD154 (CD40 Ligand) Expression","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; National Cancer Institute; American College of Rheumatology Research and Education Foundation; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Three prime untranslated region; Untranslated region; Biology; Molecular biology; CD154; Reporter gene; Response element; Messenger RNA; Promoter; Cell biology; Genetics; Gene expression; Gene; CD40; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003146428,0.0006091278,0.0004357759,0.0003608798,0.0002177978,0.0006411297,0.0001875794,0.0003381472,0.002151],"category_scores_gemma":[0.0003239988,0.000213336,0.0004311385,0.0001777368,0.0002847513,0.0002965938,0.0004210959,0.0009945983,0.001092199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005260033,"about_ca_system_score_gemma":0.0002897125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004192349,"about_ca_topic_score_gemma":0.001644314,"domain_scores_codex":[0.9995251,0.00006936525,0.00003058944,0.0001493213,0.0001232677,0.0001022616],"domain_scores_gemma":[0.9995345,0.0001106935,0.0001091317,0.00005650639,0.0001060821,0.00008314992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008306913,0.00001437516,0.0002727212,0.00003366166,0.000003640236,0.00003326336,0.00002505863,0.00003189907,0.997018,0.0002585774,0.00004438541,0.002181263],"study_design_scores_gemma":[0.00001176076,0.000181345,0.005297878,0.00001498328,0.00002219283,0.0002514695,0.00007217106,0.001108956,0.9890116,0.0002464845,0.003772969,0.000008219716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9479474,0.01358025,0.0276348,0.0005479777,0.0003130523,0.00009184665,0.001055771,0.0007274394,0.008101352],"genre_scores_gemma":[0.9798583,0.001615415,0.009498066,0.0002510471,0.00006733651,0.00007137551,0.0008090193,0.00009822475,0.007731331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002151,"threshold_uncertainty_score":0.00719583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02336894570964531,"score_gpt":0.2207525604610879,"score_spread":0.1973836147514426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}