{"id":"W1997955685","doi":"10.3816/cbc.2006.n.038","title":"Molecular Predictive Factors in Patients Receiving Trastuzumab-Based Chemotherapy for Metastatic Disease","year":2006,"lang":"en","type":"article","venue":"Clinical Breast Cancer","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"Michael Smith Health Research BC","keywords":"Medicine; Trastuzumab; Oncology; Metastatic breast cancer; Internal medicine; Breast cancer; Chemotherapy; Disease; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005182984,0.0002393978,0.0005693367,0.0001312919,0.00004602567,0.00002217887,0.0001651534,0.00008928574,0.0003387987],"category_scores_gemma":[0.0004679795,0.0002006397,0.0003176345,0.0003287561,0.0002143956,0.00006739608,0.00002400849,0.0003816605,0.000007159077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005963996,"about_ca_system_score_gemma":0.0009711814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003974168,"about_ca_topic_score_gemma":0.0000877112,"domain_scores_codex":[0.997394,0.0001645529,0.0007346552,0.0006020773,0.0005708877,0.0005338055],"domain_scores_gemma":[0.9981883,0.0005800346,0.0001384695,0.000382864,0.0002979584,0.000412437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003539648,0.001410548,0.9703088,0.0002014287,0.00008021693,0.00002055302,0.00002258681,0.000418064,0.00005047455,0.00001180735,0.001816094,0.02211974],"study_design_scores_gemma":[0.009864765,0.000507067,0.9842064,0.0003904247,0.0001159744,4.857088e-7,0.00001608568,0.002971271,0.0002991336,0.0001913758,0.001247946,0.0001890985],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924312,0.000217745,0.001399799,0.002900987,0.000310659,0.001858762,0.0006565966,0.00005884444,0.0001654469],"genre_scores_gemma":[0.9971946,0.00003188194,0.0003656282,0.001300204,0.0002632742,0.0005007174,0.0001583808,0.00007626454,0.0001089797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02193064,"threshold_uncertainty_score":0.818185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04488971125718346,"score_gpt":0.4153515785329238,"score_spread":0.3704618672757403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}