{"id":"W1997978070","doi":"10.1016/j.bmc.2010.02.054","title":"Discovery of inhibitors of brassinin oxidase based on the scaffolds of the phytoalexins brassilexin and wasalexin","year":2010,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Plant-Microbe Interactions and Immunity","field":"Agricultural and Biological Sciences","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Phytoalexin; Leptosphaeria maculans; Chemistry; Phoma; Fungus; Enzyme; Pathogenic fungus; Stereochemistry; Botany; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002500859,0.0001191194,0.0001847572,0.000006453115,0.00009311152,0.00001097606,0.0003329024,0.0001043644,0.0002737378],"category_scores_gemma":[0.0002125245,0.00003577122,0.00008979258,0.0002262047,0.0004782323,0.00005094383,0.00007612724,0.0002229243,7.573742e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000977715,"about_ca_system_score_gemma":0.00004137388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003319637,"about_ca_topic_score_gemma":0.00009541348,"domain_scores_codex":[0.9991987,0.00004205222,0.0002790297,0.0001401403,0.0002169372,0.0001230776],"domain_scores_gemma":[0.9990774,0.0004026701,0.0002668166,0.0001590371,0.00005594032,0.00003807673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004046643,0.000138286,0.005648126,0.00002924826,0.000009198769,4.244677e-7,0.0000270036,1.060282e-7,0.9925457,0.00001836316,0.0006907193,0.0008523616],"study_design_scores_gemma":[0.0001217964,0.0000728787,0.1191461,0.00018654,0.0000152099,0.00001028858,0.0003131035,0.0000177112,0.8796336,0.00002056249,0.0004029243,0.00005927904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971166,0.00005915511,6.241845e-7,0.001836503,0.0001339514,0.00007810888,0.0001569378,0.000006779563,0.0006113779],"genre_scores_gemma":[0.9995642,0.00001079337,0.000007236603,0.0001184637,0.0001186694,0.000001905652,0.00001556367,0.000001254191,0.0001618828],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.113498,"threshold_uncertainty_score":0.2997237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009749762549525205,"score_gpt":0.2002484317659581,"score_spread":0.1904986692164329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}