{"id":"W1998074314","doi":"10.1016/j.jaut.2010.07.001","title":"21-Hydroxylase epitopes are targeted by CD8 T cells in autoimmune Addison’s disease","year":2010,"lang":"en","type":"article","venue":"Journal of Autoimmunity","topic":"Adrenal Hormones and Disorders","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Epitope; Immunology; ELISPOT; Autoantibody; Human leukocyte antigen; Biology; CD8; Antibody; Autoimmunity; Autoimmune disease; T cell; Cytotoxic T cell; Antigen; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001919253,0.0003061523,0.0003093185,0.0004264889,0.0002839248,0.0003264078,0.0002423562,0.0007121246,0.002143905],"category_scores_gemma":[0.0003781871,0.0002266296,0.0002133905,0.00009953137,0.0002559176,0.0003016752,0.0002776709,0.0006465837,0.0004691829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002545604,"about_ca_system_score_gemma":0.00008165517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003069045,"about_ca_topic_score_gemma":0.0003252556,"domain_scores_codex":[0.9998326,0.00003614446,0.00001532886,0.00002941518,0.00002956999,0.00005678875],"domain_scores_gemma":[0.9998894,0.00003042297,0.00001827321,0.00001159951,0.00001382311,0.00003653899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002489399,0.0003520375,0.02273994,0.0001681575,0.00006082047,0.006033756,0.000421775,0.0005782956,0.9357216,0.0005608078,0.0007878373,0.03008571],"study_design_scores_gemma":[0.002598861,0.007226194,0.4711026,0.0001921567,0.0006528571,0.04981182,0.002531786,0.009687895,0.4074503,0.006437937,0.04219861,0.0001089836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964895,0.001464879,0.0001560097,0.0001147369,0.00005507337,0.000007989194,0.00001195273,0.00001977248,0.001680054],"genre_scores_gemma":[0.9986269,0.0003517389,0.00009771835,0.00007631913,0.0000690527,0.000006725811,0.00001544715,0.000005147296,0.0007509644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002143905,"threshold_uncertainty_score":0.007172108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006678609603410149,"score_gpt":0.2412477167333185,"score_spread":0.2345691071299084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}