{"id":"W1998100237","doi":"10.1007/s11239-012-0688-8","title":"Markers of platelet apoptosis: methodology and applications","year":2012,"lang":"en","type":"review","venue":"Journal of Thrombosis and Thrombolysis","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Metropolitan University; University of Toronto; St. Michael's Hospital","funders":"Heart and Stroke Foundation of Canada","keywords":"Apoptosis; Phosphatidylserine; Platelet; Cell biology; Cytochrome c; Flow cytometry; Programmed cell death; DNA fragmentation; Platelet activation; Fragmentation (computing); Intrinsic apoptosis; Biology; Chemistry; Immunology; Caspase; Biochemistry; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002326039,0.002260545,0.003104669,0.005306461,0.000420876,0.001933458,0.002306141,0.00220071,0.001255472],"category_scores_gemma":[0.001850543,0.0007697286,0.0009030639,0.004365608,0.002036271,0.002185379,0.001144067,0.004170379,0.001545789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001404275,"about_ca_system_score_gemma":0.001696163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001219741,"about_ca_topic_score_gemma":0.001656981,"domain_scores_codex":[0.9991316,0.0001370901,0.0001274343,0.0001767533,0.0003452848,0.00008185496],"domain_scores_gemma":[0.9984635,0.0007088032,0.0002065625,0.00006330418,0.0004728592,0.00008503396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001605038,0.000146609,0.0007350884,0.009900473,0.00009563821,0.0003263008,0.00009808621,0.0005075202,0.009878771,0.00596667,0.02044044,0.9517439],"study_design_scores_gemma":[0.00007578449,0.0004394262,0.003876395,0.003272311,0.0003947324,0.005058917,0.0002230398,0.0006125501,0.01808409,0.01005279,0.9577575,0.0001524436],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001333193,0.9978824,0.0009621833,0.0002835949,0.0002345946,0.00001006288,0.00002692745,0.00001279794,0.0004540054],"genre_scores_gemma":[0.001922365,0.9946061,0.001734087,0.0003932269,0.0003655572,0.00004373414,0.00007649332,0.000004188417,0.0008542425],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005306461,"threshold_uncertainty_score":0.01230145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08456833388544321,"score_gpt":0.3549769412038618,"score_spread":0.2704086073184185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}