{"id":"W1998104632","doi":"10.1038/ni1055","title":"Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro","year":2004,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":364,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Ontario Institute for Cancer Research; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Cell biology; Embryonic stem cell; Biology; Stem cell; Cellular differentiation; Progenitor cell; Stromal cell; T cell; Immunology; Immune system; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005928738,0.000623156,0.0004504826,0.0006859201,0.000335189,0.0006135546,0.0006135707,0.0004711962,0.002562578],"category_scores_gemma":[0.0003635414,0.0004419692,0.0007529853,0.0004257198,0.0003684916,0.0003190977,0.0006454437,0.001847326,0.001831094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004085183,"about_ca_system_score_gemma":0.0004140161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007161529,"about_ca_topic_score_gemma":0.001081188,"domain_scores_codex":[0.999585,0.00008285016,0.0000840663,0.00005979185,0.00009039853,0.00009795912],"domain_scores_gemma":[0.9995162,0.0001857718,0.00005482854,0.00008072557,0.00006196555,0.0001004569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008067623,0.00002611317,0.0001013444,0.0000479691,0.000005178756,0.00007328385,0.00003645175,0.00008236108,0.9981521,0.0003421462,0.00005876591,0.0009934922],"study_design_scores_gemma":[0.00001930843,0.00007849987,0.000753662,0.000008028572,0.00001149148,0.00008355431,0.000009112759,0.000346913,0.9963684,0.00006021929,0.002257769,0.000002919657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8745163,0.004673198,0.09084145,0.0003354402,0.0002902432,0.001724889,0.00514943,0.0008667731,0.02160231],"genre_scores_gemma":[0.9489725,0.002532407,0.03053588,0.0001922432,0.00008413653,0.0007144829,0.004956074,0.0002685655,0.01174362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002562578,"threshold_uncertainty_score":0.008572698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006379103896825768,"score_gpt":0.2183055776820252,"score_spread":0.2119264737851995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}