{"id":"W1998111191","doi":"10.1002/ijc.24398","title":"Genistein depletes telomerase activity through cross‐talk between genetic and epigenetic mechanisms","year":2009,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Fondation pour la Recherche Médicale; McMaster University; Glenn Foundation for Medical Research","keywords":"Genistein; Epigenetics; Telomerase; Genetics; Biology; Internal medicine; Cancer research; Medicine; Oncology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000985689,0.0003009203,0.0002605983,0.0001651539,0.00008708819,0.0001751084,0.0001433591,0.0001941785,0.0007050656],"category_scores_gemma":[0.0000569853,0.0001206743,0.0002286638,0.0001145207,0.0001290706,0.0001089651,0.0001485415,0.0003601472,0.0001491688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002036672,"about_ca_system_score_gemma":0.000152213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004163379,"about_ca_topic_score_gemma":0.001402848,"domain_scores_codex":[0.9999204,0.000009651183,0.000006672727,0.00002351592,0.00002228363,0.00001749144],"domain_scores_gemma":[0.9999605,0.000008117608,0.0000131183,0.00000652334,0.000004063651,0.000007696312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006094912,0.00001420953,0.0001139656,0.00002333389,0.000006669943,0.00001607331,0.00000391522,0.00002661286,0.9981582,0.00003987751,0.00001212407,0.001524123],"study_design_scores_gemma":[0.00001644674,0.0002505461,0.005066628,0.000003456603,0.00002406939,0.0001212736,0.000006875508,0.0003005415,0.9918052,0.00003860603,0.002364247,0.000002053504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894143,0.005505796,0.002898123,0.0001123458,0.00003147933,0.00002953091,0.0002448487,0.0001338505,0.001629681],"genre_scores_gemma":[0.9915816,0.002988953,0.001831189,0.00008076505,0.00001604809,0.00003456429,0.0003827301,0.00001676866,0.003067351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007050656,"threshold_uncertainty_score":0.002358675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02254342845196908,"score_gpt":0.3538634291651824,"score_spread":0.3313200007132133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}