{"id":"W1998111961","doi":"10.1016/j.exger.2006.06.041","title":"Genetic and molecular characterization of CLK-1/mCLK1, a conserved determinant of the rate of aging","year":2006,"lang":"en","type":"review","venue":"Experimental Gerontology","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"McGill University","keywords":"Biology; Caenorhabditis elegans; Genetics; Gene; Mechanism (biology); Conserved sequence; Calorie restriction; Peptide sequence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009299784,0.001167079,0.00173655,0.001473782,0.0002595002,0.001130348,0.001568538,0.001223633,0.001454575],"category_scores_gemma":[0.0008385385,0.0003608519,0.0003152298,0.001432547,0.0009410806,0.001264824,0.0005697118,0.002259264,0.001734836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001229988,"about_ca_system_score_gemma":0.001464936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001502567,"about_ca_topic_score_gemma":0.001633284,"domain_scores_codex":[0.9997601,0.00001857539,0.00002862743,0.00007665133,0.00009592872,0.00002015619],"domain_scores_gemma":[0.9994338,0.0001605744,0.00009998378,0.00003427319,0.0002086525,0.00006270403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000293798,0.0001291601,0.0008720027,0.008689759,0.00009387535,0.0004093554,0.00006447991,0.0008678169,0.06110306,0.008890098,0.02278381,0.8958027],"study_design_scores_gemma":[0.00007434458,0.0001895884,0.005110116,0.001098611,0.0002673098,0.003654944,0.00008564299,0.0004833163,0.03767709,0.005355682,0.9459326,0.00007079249],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009311717,0.9959371,0.001153434,0.0004125013,0.0002411677,0.000007651235,0.0000712749,0.00002295591,0.001222785],"genre_scores_gemma":[0.004485527,0.992203,0.001258556,0.0002631229,0.0002204662,0.00001502039,0.0001868624,0.00000571723,0.001361748],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00173655,"threshold_uncertainty_score":0.008924246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02505960853616332,"score_gpt":0.2968659096681253,"score_spread":0.2718063011319619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}