{"id":"W1998184086","doi":"10.1091/mbc.e12-10-0730","title":"Inactivation of<i>Caenorhabditis elegans</i>aminopeptidase DNPP-1 restores endocytic sorting and recycling in<i>tat-1</i>mutants","year":2013,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; National Institutes of Health; McGill University; Howard Hughes Medical Institute","keywords":"Endocytic cycle; Biology; Cell biology; Endosome; Caenorhabditis elegans; Mutant; Rab; Protein targeting; Transport protein; Aminopeptidase; Biochemistry; Endocytosis; Membrane protein; GTPase; Membrane; Cell; Intracellular; Amino acid","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001036538,0.000751331,0.0002459103,0.0003497054,0.0003613736,0.0003745808,0.0004743031,0.0004912766,0.0006723878],"category_scores_gemma":[0.0001470886,0.0003232562,0.0003493936,0.0001133666,0.0004183839,0.0001805201,0.0003391409,0.0007708994,0.0003238361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007789825,"about_ca_system_score_gemma":0.0004585362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004534945,"about_ca_topic_score_gemma":0.005253142,"domain_scores_codex":[0.9997986,0.000015183,0.00003687025,0.00004474548,0.00006393878,0.00004077014],"domain_scores_gemma":[0.9997274,0.00002738163,0.00009419383,0.0000260446,0.00002734557,0.00009768359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002300865,0.00001102111,0.00009573994,0.00001845079,0.000003493295,0.00005014948,0.000006552422,0.0000549349,0.9994668,0.00004162711,0.00001192789,0.0002163343],"study_design_scores_gemma":[0.00001294536,0.00007517397,0.005603859,0.00001086891,0.0000191742,0.0002513,0.00003109796,0.001360256,0.9915399,0.00004314861,0.001041852,0.00001039788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967295,0.0003372425,0.001624298,0.00005471161,0.00002378914,0.00002076272,0.0003847923,0.0001257122,0.0006991945],"genre_scores_gemma":[0.9944836,0.0003630322,0.002006246,0.00005577653,0.000005876118,0.00003746666,0.0004285184,0.00008299701,0.00253628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004534945,"threshold_uncertainty_score":0.00901711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004914166497126627,"score_gpt":0.2164622336367381,"score_spread":0.2115480671396115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}