{"id":"W1998216377","doi":"10.1038/cgt.2012.96","title":"Cancer upregulated gene 2, a novel oncogene, confers resistance to oncolytic vesicular stomatitis virus through STAT1-OASL2 signaling","year":2013,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Vesicular stomatitis virus; Oncolytic virus; STAT1; Biology; Oncogene; Gene knockdown; Cancer cell; Virology; Gene silencing; Transfection; RNA interference; Signal transduction; Virus; Cancer research; Cell culture; Molecular biology; Cell; Cell biology; Gene; Interferon; Cancer; RNA; Cell cycle; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009426744,0.0003464152,0.0001689786,0.0003198006,0.0001967652,0.0002766895,0.0001476946,0.000190763,0.0009744783],"category_scores_gemma":[0.00007285427,0.0001228118,0.000223928,0.0001596686,0.0002507891,0.0001870722,0.0001578064,0.0005372959,0.0002608275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004715331,"about_ca_system_score_gemma":0.0002766792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005165829,"about_ca_topic_score_gemma":0.001052022,"domain_scores_codex":[0.9999202,0.000009022619,0.000006057628,0.00001408732,0.00002741736,0.00002315183],"domain_scores_gemma":[0.9999588,0.000008725799,0.00000996834,0.000006594448,0.000003399274,0.00001239623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000879005,0.00003267256,0.0002004895,0.000009160324,0.000002770588,0.00009322925,0.00001022121,0.00007058317,0.9983505,0.000291386,0.00006803108,0.0007830102],"study_design_scores_gemma":[0.00003625089,0.0002824703,0.0028121,0.000002263385,0.00002041964,0.0007901961,0.00002626132,0.001709652,0.9897321,0.0001040151,0.004479172,0.000005156958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995138,0.0004509144,0.001842446,0.0001398471,0.00004125528,0.00002800402,0.0002777053,0.0001190184,0.001962854],"genre_scores_gemma":[0.9941595,0.0003534685,0.001448663,0.00004258733,0.000008391384,0.00002049506,0.0006196902,0.00001980329,0.003327333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009744783,"threshold_uncertainty_score":0.003421247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03071657539836243,"score_gpt":0.3232019711619624,"score_spread":0.2924853957635999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}