{"id":"W1998251684","doi":"10.1182/blood-2012-04-422550","title":"Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Caprion (Canada); Université de Montréal","funders":"National Institute on Drug Abuse; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Cytotoxic T cell; Biology; CD8; Immunology; Chronic infection; T cell; Viral load; Viral replication; Virology; Immune system; Virus; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000080775,0.0001562003,0.0002268451,0.0003032069,0.0001521488,0.0002912606,0.00007692124,0.0002097205,0.00110874],"category_scores_gemma":[0.0002009373,0.0001105567,0.00008446737,0.0001345181,0.0002009302,0.0001583495,0.0001399651,0.0002768264,0.0001846759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001088026,"about_ca_system_score_gemma":0.00006932898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001505815,"about_ca_topic_score_gemma":0.0001819359,"domain_scores_codex":[0.9999204,0.00000954535,0.000006368095,0.00002175413,0.00001160748,0.00003049922],"domain_scores_gemma":[0.9999202,0.00001595528,0.00001462993,0.0000110054,0.00001150466,0.00002658322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004378272,0.0000564246,0.01070118,0.00003390024,0.000005459592,0.0001908099,0.0001461189,0.00003495974,0.9846616,0.00005024576,0.00001937813,0.003662102],"study_design_scores_gemma":[0.0001165108,0.002799184,0.610949,0.00003182646,0.0000711343,0.006051605,0.001015067,0.0008122596,0.375029,0.0006948837,0.002404955,0.0000247027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991904,0.0003517056,0.0001515477,0.000008126128,0.000001914144,0.000007302563,0.00005621838,0.000005737425,0.0002271938],"genre_scores_gemma":[0.99909,0.0001928336,0.000224402,0.00001479256,0.000007139004,0.00001919473,0.0001106039,0.000003065868,0.0003380288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00110874,"threshold_uncertainty_score":0.003709078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02034497284446869,"score_gpt":0.2215474963758479,"score_spread":0.2012025235313793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}