{"id":"W1998295128","doi":"10.1007/s00280-009-0965-1","title":"Pre-clinical evaluation of Rh2 in PC-3 human xenograft model for prostate cancer in vivo: formulation, pharmacokinetics, biodistribution and efficacy","year":2009,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Ginseng Biological Effects and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; University of British Columbia; University of British Columbia Hospital; Vancouver General Hospital","funders":"Health Canada","keywords":"Biodistribution; Pharmacokinetics; Prostate cancer; In vivo; Medicine; Cancer; Prostate; Pharmacology; Distribution (mathematics); Oncology; Internal medicine; Biology; Mathematics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004704173,0.0001147702,0.0001873059,0.00003776656,0.00004342939,0.000005415592,0.00005861019,0.0001423229,0.00003473007],"category_scores_gemma":[0.00001428473,0.0001029676,0.00003585572,0.00007929859,0.00009269684,0.000005339548,0.00001267425,0.00007988609,3.685862e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002463494,"about_ca_system_score_gemma":0.00006337526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003186957,"about_ca_topic_score_gemma":0.00006707339,"domain_scores_codex":[0.9991025,0.00007853052,0.0003010818,0.0002977465,0.0000541736,0.0001659409],"domain_scores_gemma":[0.9996361,0.00003084092,0.0001131651,0.00006778625,0.0001048231,0.00004735842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005109787,0.0002141883,0.01019828,0.00002808453,0.00002694258,6.276497e-8,0.0001220182,0.003979396,0.9080779,0.00003831727,0.0004774041,0.07632641],"study_design_scores_gemma":[0.01516147,0.0007935863,0.1308617,0.00003931785,0.0001099267,8.608385e-7,0.000009988001,0.2293532,0.6177586,0.001288714,0.004337688,0.0002849383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944833,0.002725823,0.0005913088,0.0008901396,0.00004967994,0.001096315,0.0001420976,0.000005134944,0.0000162355],"genre_scores_gemma":[0.9925088,0.006190866,0.00008502636,0.0006996351,0.0001112448,0.00030087,0.00006692931,0.00000659534,0.00003002676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2903194,"threshold_uncertainty_score":0.4198898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04347664029488311,"score_gpt":0.4315106341974881,"score_spread":0.388033993902605,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}