{"id":"W1998326416","doi":"10.1007/s11606-014-2880-3","title":"Using Value-of-Information Methods when the Disease Is Rare and the Treatment Is Expensive—The Example of Hemophilia A","year":2014,"lang":"en","type":"article","venue":"Journal of General Internal Medicine","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Clinical Evaluative Sciences; Hospital for Sick Children; Public Health Ontario; University of Toronto; Toronto Public Health","funders":"","keywords":"Medicine; Value (mathematics); Disease; Intensive care medicine; MEDLINE; Internal medicine; Statistics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02965976,0.001644101,0.001904937,0.004856491,0.0009529713,0.004781849,0.002214247,0.002656292,0.005007903],"category_scores_gemma":[0.1370909,0.0004846962,0.001547347,0.005386917,0.001391252,0.006128198,0.002239928,0.004184071,0.0005706346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001781888,"about_ca_system_score_gemma":0.003263656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007001,"about_ca_topic_score_gemma":0.007019419,"domain_scores_codex":[0.9821124,0.01375709,0.0006828401,0.001130903,0.001993456,0.0003233337],"domain_scores_gemma":[0.7879552,0.1963295,0.004124585,0.005745143,0.004849037,0.0009964248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.002005102,0.001070214,0.04732392,0.001854808,0.002275826,0.001175381,0.001109198,0.0709606,0.001201624,0.2441445,0.0245204,0.6023584],"study_design_scores_gemma":[0.0002307755,0.0003577826,0.005630352,0.0005639303,0.0005600825,0.0006704054,0.0004765991,0.4051754,0.001788508,0.5668947,0.01746087,0.0001907043],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.06805159,0.01132374,0.8774905,0.01638279,0.0009104433,0.0004943746,0.002402203,0.000585574,0.02235881],"genre_scores_gemma":[0.6179645,0.004387146,0.3704102,0.001198859,0.0008596265,0.0002777943,0.001120783,0.0001811196,0.003599984],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.02965976,"threshold_uncertainty_score":0.1568577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08533863940545351,"score_gpt":0.4051397151826003,"score_spread":0.3198010757771468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}