{"id":"W1998338131","doi":"10.1016/j.neuint.2009.02.020","title":"Astrocytes are a major target in thiamine deficiency and Wernicke's encephalopathy","year":2009,"lang":"en","type":"review","venue":"Neurochemistry International","topic":"Alcoholism and Thiamine Deficiency","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Excitotoxicity; Wernicke Encephalopathy; Glutamate receptor; Neuroscience; Wernicke's encephalopathy; Astrocyte; Glutamine synthetase; Encephalopathy; Brain damage; Biology; Thiamine; Glutamine; Pathology; Medicine; Thiamine deficiency; Central nervous system; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002322672,0.0006525179,0.001046824,0.001255153,0.0002039968,0.0005229635,0.0004228727,0.0007388467,0.001547081],"category_scores_gemma":[0.000213922,0.000197854,0.0002452105,0.001357862,0.0002597556,0.0005972457,0.0003841242,0.000656891,0.001021986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003422801,"about_ca_system_score_gemma":0.0006831823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001505784,"about_ca_topic_score_gemma":0.003338612,"domain_scores_codex":[0.9999323,0.000009065241,0.00001562631,0.00001091748,0.00002302642,0.000009079673],"domain_scores_gemma":[0.9998779,0.00003258565,0.00002889353,0.000003499498,0.00004424554,0.00001288541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002738721,0.00007897806,0.0005641609,0.01373266,0.0001301476,0.001038736,0.00005696176,0.0002549535,0.008685886,0.001590256,0.01839409,0.9551993],"study_design_scores_gemma":[0.00009119898,0.0002414541,0.005088323,0.002914187,0.0005581044,0.006724145,0.0002141173,0.0001735043,0.00421334,0.002509589,0.9772344,0.00003772333],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003749255,0.9984889,0.00009612973,0.0001891408,0.0001531217,0.000002811167,0.00001610034,0.000004464,0.0006742895],"genre_scores_gemma":[0.002053484,0.9967439,0.0001652819,0.0000884212,0.0001664834,0.000004425671,0.00003389533,6.14203e-7,0.0007435637],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001547081,"threshold_uncertainty_score":0.005175471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0241081022262246,"score_gpt":0.3193073739495556,"score_spread":0.295199271723331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}