{"id":"W1998338131","doi":"10.1016/j.neuint.2009.02.020","title":"Astrocytes are a major target in thiamine deficiency and Wernicke's encephalopathy","year":2009,"lang":"en","type":"review","venue":"Neurochemistry International","topic":"Alcoholism and Thiamine Deficiency","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Excitotoxicity; Wernicke Encephalopathy; Glutamate receptor; Neuroscience; Wernicke's encephalopathy; Astrocyte; Glutamine synthetase; Encephalopathy; Brain damage; Biology; Thiamine; Glutamine; Pathology; Medicine; Thiamine deficiency; Central nervous system; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001456292,0.0004964551,0.001138248,0.000256482,0.00004531167,0.00005305848,0.0004030792,0.0003024507,0.0002158069],"category_scores_gemma":[0.0004534865,0.000419911,0.0002619487,0.0002707507,0.0001102114,0.00008692044,0.0001431181,0.0007849754,0.00004243843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000131286,"about_ca_system_score_gemma":0.0002253741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004479935,"about_ca_topic_score_gemma":9.350747e-7,"domain_scores_codex":[0.9976426,0.00003453686,0.0006863176,0.0007512496,0.0005398697,0.0003453672],"domain_scores_gemma":[0.9988911,0.0001106279,0.0003932539,0.0003456872,0.0001055285,0.0001538369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003107268,0.002508183,0.007338953,0.04175445,0.000279399,0.006002062,0.0003231065,0.000003249009,0.001172316,0.0006306666,0.004673719,0.9350032],"study_design_scores_gemma":[0.00159115,0.0002141955,0.002071285,0.01055479,0.0004275652,0.003843234,0.00006089083,0.00005792745,0.0002365907,0.00005109699,0.9802532,0.0006380453],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003792454,0.9820307,0.00001771983,0.0001902725,0.0003039811,0.0003621175,0.0001293802,0.00006242519,0.01311089],"genre_scores_gemma":[0.007488369,0.9891272,0.00025629,0.0001831337,0.0004760482,0.00005813991,0.000517778,0.00004433297,0.001848751],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9755795,"threshold_uncertainty_score":0.9998253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0241081022262246,"score_gpt":0.3193073739495556,"score_spread":0.295199271723331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}