{"id":"W1998340024","doi":"10.1107/s090744490301165x","title":"Lessons from an aged, dried crystal of T<sub>6</sub>human insulin","year":2003,"lang":"en","type":"article","venue":"Acta Crystallographica Section D Biological Crystallography","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"National Institute of General Medical Sciences","keywords":"Crystallography; Random hexamer; Chemistry; Hydrogen bond; Zinc; Crystal structure; Carboxylate; Dimer; Side chain; Ion; Coordination sphere; Stereochemistry; Molecule; Organic chemistry; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002513514,0.0003003608,0.0005263183,0.0002416799,0.00111808,0.001172321,0.001291528,0.001362852,0.002750781],"category_scores_gemma":[0.001655119,0.0004966921,0.0003342279,0.0004506941,0.001546305,0.001563538,0.0008349144,0.002734643,0.0009051947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00076033,"about_ca_system_score_gemma":0.0004494863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006855997,"about_ca_topic_score_gemma":0.007816954,"domain_scores_codex":[0.9997872,0.0000248785,0.00001476669,0.00004675497,0.00009717142,0.00002928302],"domain_scores_gemma":[0.9995223,0.00009648809,0.00009165477,0.00006644647,0.0001434814,0.00007967381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002808531,0.0005865211,0.04034403,0.003076831,0.0003083492,0.05781906,0.006159836,0.01595762,0.6709839,0.04160498,0.07945092,0.08089942],"study_design_scores_gemma":[0.0004956936,0.00108011,0.08839982,0.000545676,0.000408284,0.06346381,0.01439777,0.02286034,0.3940976,0.09270985,0.3209502,0.0005908496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.908321,0.0146209,0.009227468,0.02426697,0.002258348,0.00005912056,0.001728114,0.0005681756,0.03895],"genre_scores_gemma":[0.963186,0.007665548,0.01094185,0.003954107,0.0007242474,0.00002373942,0.001395033,0.0003089908,0.01180042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006855997,"threshold_uncertainty_score":0.01363218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02182463628204384,"score_gpt":0.2526428377767876,"score_spread":0.2308182014947438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}