{"id":"W1998382046","doi":"10.1016/j.biomaterials.2011.08.061","title":"Induction of immunotolerance via mPEG grafting to allogeneic leukocytes","year":2011,"lang":"en","type":"article","venue":"Biomaterials","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Canadian Blood Services","funders":"Canadian Institutes of Health Research","keywords":"Allorecognition; PEGylation; In vivo; Splenocyte; Immunology; Mixed lymphocyte reaction; Peripheral blood mononuclear cell; In vitro; Pharmacology; T cell; Biology; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002059672,0.000515347,0.0001810607,0.0002537852,0.0001415311,0.0002536118,0.0001736193,0.0003073141,0.0008130539],"category_scores_gemma":[0.0001252454,0.0001137925,0.0002777644,0.0001434555,0.0001833956,0.0002658273,0.000273495,0.0005095697,0.0001857285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001737367,"about_ca_system_score_gemma":0.0001364925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001430505,"about_ca_topic_score_gemma":0.0002454993,"domain_scores_codex":[0.9998758,0.00002196875,0.000009876911,0.00001729901,0.00002693278,0.00004813031],"domain_scores_gemma":[0.9999018,0.00002673527,0.00003187367,0.0000174261,0.000007379315,0.00001479069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001277532,0.00004258532,0.00008161452,0.00001556699,0.000002954319,0.00003929592,0.0000145849,0.00008225808,0.9984566,0.0001880116,0.000008520266,0.0009403073],"study_design_scores_gemma":[0.00001046567,0.0003934429,0.0007760484,0.000003213143,0.00001098348,0.00007252877,0.00001072003,0.0003567425,0.9978045,0.00004065187,0.000519101,0.000001622031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996046,0.0004290437,0.002197378,0.00002765861,0.00002077271,0.00003440759,0.00004110092,0.00002454676,0.001179121],"genre_scores_gemma":[0.9977616,0.00028136,0.0008355636,0.00002218613,0.00001033721,0.00001971432,0.00004702997,0.000009426928,0.001012824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008130539,"threshold_uncertainty_score":0.002719998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03307333224029589,"score_gpt":0.2469355692929565,"score_spread":0.2138622370526606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}