{"id":"W1998382046","doi":"10.1016/j.biomaterials.2011.08.061","title":"Induction of immunotolerance via mPEG grafting to allogeneic leukocytes","year":2011,"lang":"en","type":"article","venue":"Biomaterials","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Canadian Blood Services","funders":"Canadian Institutes of Health Research","keywords":"Allorecognition; PEGylation; In vivo; Splenocyte; Immunology; Mixed lymphocyte reaction; Peripheral blood mononuclear cell; In vitro; Pharmacology; T cell; Biology; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000405937,0.000183465,0.0003664353,0.0001665378,0.0001263235,0.00001021864,0.0002696995,0.0002088191,0.001376523],"category_scores_gemma":[0.00005749905,0.0001597989,0.00009069057,0.0001562895,0.0001463834,0.0001084864,0.00007411868,0.00001960872,0.0005530391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002261498,"about_ca_system_score_gemma":0.00003460982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005218313,"about_ca_topic_score_gemma":0.000003101334,"domain_scores_codex":[0.9986339,0.0002858864,0.000516756,0.0002253401,0.00002953134,0.0003085424],"domain_scores_gemma":[0.9993047,0.00004218099,0.0002146972,0.000351568,0.00007403978,0.00001286804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001450259,0.00008955615,0.0003147394,0.00001770489,0.0001648228,0.000001300498,0.001368453,1.911957e-7,0.9880052,0.00008465226,0.00009833175,0.008404749],"study_design_scores_gemma":[0.0006061852,0.0003174937,0.03025036,0.00005142634,0.0000185303,0.00005568027,0.00009461935,5.253789e-8,0.9613467,0.00006378402,0.007016663,0.0001784386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937882,0.003375644,0.000204622,0.00002554304,0.001977018,0.0002885795,0.00002027941,0.00008497488,0.0002351094],"genre_scores_gemma":[0.9987382,0.00008995041,0.0005010839,0.00008015862,0.00003036565,0.00004430044,0.00002512831,0.00002325528,0.0004675029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02993562,"threshold_uncertainty_score":0.9995363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03307333224029589,"score_gpt":0.2469355692929565,"score_spread":0.2138622370526606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}