{"id":"W1998483228","doi":"10.2165/00007256-200838020-00004","title":"Mechanotransduction in Human Bone","year":2008,"lang":"en","type":"review","venue":"Sports Medicine","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary; Vancouver Coastal Health; Vancouver Coastal Health Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; Canadian Space Agency; Michael Smith Health Research BC; Calgary Foundation","keywords":"Mechanotransduction; Cytoskeleton; Cell biology; Bone remodeling; Integrin; Intracellular; Bone cell; Signalling; Neuroscience; Biology; Biophysics; Chemistry; Cell; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008509022,0.001209979,0.001869224,0.001882116,0.0003738979,0.001184602,0.001468011,0.001705877,0.002693868],"category_scores_gemma":[0.0008888376,0.0004058641,0.0004605106,0.002285855,0.0009772847,0.001731679,0.0008257016,0.002362289,0.002487175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006312029,"about_ca_system_score_gemma":0.001010485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00112961,"about_ca_topic_score_gemma":0.002871877,"domain_scores_codex":[0.9998111,0.00002484936,0.00002881307,0.0000399623,0.00007655617,0.00001879363],"domain_scores_gemma":[0.9996583,0.0001558136,0.00004402527,0.0000122776,0.00009306577,0.00003648974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008527535,0.00006135344,0.0001619134,0.009006727,0.00006349303,0.0003201152,0.00004365694,0.0004827673,0.003571778,0.003892125,0.04149443,0.9408162],"study_design_scores_gemma":[0.00002759411,0.00006415044,0.00072094,0.001763161,0.0000937979,0.001485612,0.00006186982,0.0001263597,0.0006968239,0.002944326,0.9919978,0.00001770128],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009128029,0.9978842,0.0003377249,0.000294571,0.0006082925,0.000003486277,0.00001113898,0.000007504499,0.0007619019],"genre_scores_gemma":[0.0005562893,0.9969431,0.0003701878,0.0003468907,0.0006671284,0.000007185337,0.00002130533,0.000001767593,0.001086178],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002693868,"threshold_uncertainty_score":0.009011865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02608507694904691,"score_gpt":0.3228129595524246,"score_spread":0.2967278826033777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}