{"id":"W1998483228","doi":"10.2165/00007256-200838020-00004","title":"Mechanotransduction in Human Bone","year":2008,"lang":"en","type":"review","venue":"Sports Medicine","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary; Vancouver Coastal Health; Vancouver Coastal Health Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; Canadian Space Agency; Michael Smith Health Research BC; Calgary Foundation","keywords":"Mechanotransduction; Cytoskeleton; Cell biology; Bone remodeling; Integrin; Intracellular; Bone cell; Signalling; Neuroscience; Biology; Biophysics; Chemistry; Cell; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001517358,0.0002812411,0.0007856438,0.0002181805,0.00005570268,0.000002791095,0.0001186814,0.0003274662,0.0003098881],"category_scores_gemma":[0.00002477521,0.0002298038,0.0002244395,0.0001775355,0.00004615674,0.000001942813,0.00003343467,0.0002758013,0.000007566855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003463434,"about_ca_system_score_gemma":0.00008554011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005154573,"about_ca_topic_score_gemma":0.0000295851,"domain_scores_codex":[0.9985942,0.00003590471,0.0005578087,0.0004305103,0.0001791756,0.0002024032],"domain_scores_gemma":[0.9992585,0.000003843872,0.0002098706,0.0004180846,0.00003642182,0.00007326186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005960766,0.0000889779,0.000001269661,0.00115308,0.00005491074,0.0001642816,0.00003330556,6.198745e-7,0.003105765,0.0003218674,0.007595092,0.9874749],"study_design_scores_gemma":[0.000193082,0.0001242001,0.000001216186,0.003372589,0.00009516077,0.0004825503,0.00001635845,0.000001128922,0.0001568,0.00003990956,0.9953112,0.0002058221],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000742039,0.9965361,0.0001752058,0.00003745694,0.0007954568,0.0003333292,0.0000064265,0.00001126576,0.00203054],"genre_scores_gemma":[0.0004479165,0.9941425,0.00002081496,0.00004623149,0.00100189,0.0000441202,0.001611959,0.00004996342,0.00263462],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9877161,"threshold_uncertainty_score":0.9371129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02608507694904691,"score_gpt":0.3228129595524246,"score_spread":0.2967278826033777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}