{"id":"W1998512738","doi":"10.1081/scc-100000584","title":"RESOLUTION OF CHIRAL ALIPHATIC AND ARYLALKYL AMINES USING IMMOBILIZED<i>CANDIDA ANTARCTICA</i>LIPASE AND ISOLATION OF THEIR R- AND S-ENANTIOMERS","year":2001,"lang":"en","type":"article","venue":"Synthetic Communications","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Novo Nordisk","keywords":"Chemistry; Candida antarctica; Enantiomer; Lipase; Enantiomeric excess; Resolution (logic); Amine gas treating; Yield (engineering); Organic chemistry; Chromatography; Enantioselective synthesis; Enzyme; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003293639,0.000914034,0.0005010577,0.0002758889,0.0002372977,0.000379173,0.0005019808,0.0004847955,0.001032753],"category_scores_gemma":[0.0004007856,0.000256431,0.0005506177,0.000360388,0.0002320065,0.0002125456,0.0004496299,0.0006745954,0.0009118506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002897967,"about_ca_system_score_gemma":0.0003217723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001727319,"about_ca_topic_score_gemma":0.00224802,"domain_scores_codex":[0.9997448,0.00004602983,0.00002103897,0.00003585004,0.00008888352,0.00006329995],"domain_scores_gemma":[0.999848,0.00003149905,0.00002826207,0.0000208573,0.0000480446,0.00002335831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004153066,0.000007038199,0.0000594825,0.00004075788,0.000005113269,0.0000692147,0.00001457099,0.00003789164,0.99764,0.00004788326,0.00006013248,0.00197641],"study_design_scores_gemma":[0.000005083022,0.00003268111,0.0002812573,0.000002841184,0.000005023362,0.0001252444,0.0000109857,0.0001916666,0.9982536,0.00002471364,0.001061727,0.000005053075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9449775,0.006543052,0.03346883,0.0005567484,0.0001826926,0.0001498864,0.001000841,0.0004146099,0.01270585],"genre_scores_gemma":[0.9350173,0.006880168,0.03763669,0.0002876142,0.00006717473,0.0001278651,0.002356261,0.0002008139,0.01742608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001727319,"threshold_uncertainty_score":0.003454864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01929943035778687,"score_gpt":0.2701750272542539,"score_spread":0.250875596896467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}