{"id":"W1998528294","doi":"10.1371/journal.pone.0043050","title":"NRFL-1, the C. elegans NHERF Orthologue, Interacts with Amino Acid Transporter 6 (AAT-6) for Age-Dependent Maintenance of AAT-6 on the Membrane","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Core Research for Evolutional Science and Technology; Institute of Genetics; National Cancer Institute; Japan Science and Technology Agency; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology","keywords":"PDZ domain; Caenorhabditis elegans; Cell biology; Biology; Membrane protein; Immunoprecipitation; Transmembrane protein; Molecular biology; Biochemistry; Gene; Membrane; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006866543,0.0004086106,0.0002718766,0.0002476164,0.0002510372,0.000136712,0.0002080066,0.0003947993,0.001029107],"category_scores_gemma":[0.00008606398,0.000148432,0.0004060779,0.00009560517,0.0001184387,0.0002556213,0.0002779114,0.0003336285,0.0006222545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000265223,"about_ca_system_score_gemma":0.0001118302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005921383,"about_ca_topic_score_gemma":0.001122332,"domain_scores_codex":[0.999904,0.000005270226,0.000006298125,0.000038636,0.00002845077,0.00001719492],"domain_scores_gemma":[0.9999379,0.000006663432,0.00002301427,0.00000461152,0.00001004013,0.00001783919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002342266,0.000007070517,0.0003971256,0.00003621716,0.000002440061,0.0001100864,0.000007611921,0.00002232438,0.998487,0.0000301225,0.00003627159,0.0008403825],"study_design_scores_gemma":[0.00000944504,0.0001458518,0.03695327,0.00002419219,0.00002478302,0.002326707,0.0000533473,0.002013321,0.9509879,0.00006130969,0.007382503,0.00001739233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918017,0.001778883,0.004085882,0.0001147827,0.00002523262,0.00002368546,0.0009420734,0.000147413,0.001080347],"genre_scores_gemma":[0.9792371,0.001364811,0.01005396,0.00008302278,0.00001067579,0.00004128243,0.002486421,0.00003550683,0.006687219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001029107,"threshold_uncertainty_score":0.003442705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03352464153444282,"score_gpt":0.2165698905858947,"score_spread":0.1830452490514519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}