{"id":"W1998567489","doi":"10.1007/s00395-009-0035-1","title":"Cardiac dysfunction in an animal model of neonatal asphyxia is associated with increased degradation of MLC1 by MMP-2","year":2009,"lang":"en","type":"article","venue":"Basic Research in Cardiology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Saskatchewan Health Research Foundation; Heart and Stroke Foundation of Canada","keywords":"Cardiac function curve; Stroke volume; Cardiac output; Ventilation (architecture); Medicine; Cardiac index; Asphyxia; Hypoxia (environmental); Internal medicine; Room air distribution; Anesthesia; Endocrinology; Oxygen; Cardiology; Heart rate; Chemistry; Hemodynamics; Heart failure; Blood pressure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003339683,0.0006396957,0.0004585839,0.0009330608,0.0003213134,0.0003264725,0.0004196735,0.000485672,0.001534791],"category_scores_gemma":[0.0003692404,0.0002904077,0.0003004582,0.0003197314,0.0007244249,0.0004319266,0.0002337734,0.001348999,0.0001907237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005375742,"about_ca_system_score_gemma":0.0002863371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005650363,"about_ca_topic_score_gemma":0.0008631916,"domain_scores_codex":[0.9998379,0.00003297272,0.00001980034,0.00003006203,0.00004505367,0.00003427613],"domain_scores_gemma":[0.9994842,0.0001024995,0.0001797243,0.0000717068,0.00002649566,0.000135512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002162518,0.0001726305,0.0008900655,0.00009991621,0.00002820616,0.001045372,0.00005281675,0.0001470774,0.9934557,0.00035113,0.000115041,0.001479511],"study_design_scores_gemma":[0.0001286339,0.001596046,0.02583503,0.00003837903,0.0001011923,0.00358104,0.0001689433,0.002211869,0.964766,0.0002403496,0.001316233,0.00001629157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941249,0.00180245,0.00216911,0.0002269844,0.0000634289,0.00003857257,0.0003746671,0.0000599317,0.001139955],"genre_scores_gemma":[0.9942755,0.00132975,0.001892111,0.00008989205,0.00002660533,0.00009710012,0.0005136956,0.00001965297,0.001755718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001534791,"threshold_uncertainty_score":0.005134404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03565726175809358,"score_gpt":0.3064259488107601,"score_spread":0.2707686870526665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}