{"id":"W1998605542","doi":"10.1016/j.amjopharm.2011.02.003","title":"Potentially Procholinergic Effects of Medications Commonly Used in Older Adults","year":2011,"lang":"en","type":"article","venue":"˜The œAmerican journal of geriatric pharmacotherapy","topic":"Cholinesterase and Neurodegenerative Diseases","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Saint Vincent University; Carleton University; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Butyrylcholinesterase; Cholinesterase; Pharmacology; Acetylcholinesterase; Medicine; Galantamine; Drug; Risperidone; Anticholinergic; Donepezil; Dementia; Disease; Internal medicine; Aché; Chemistry; Psychiatry; Enzyme; Biochemistry; Schizophrenia (object-oriented programming)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000369297,0.0004050701,0.0005732728,0.0004999387,0.000379587,0.0005414258,0.0001569864,0.0006083921,0.004071499],"category_scores_gemma":[0.003112946,0.0001196439,0.0005632344,0.0004964025,0.0001340109,0.0004337129,0.0002424817,0.0005072179,0.0002793989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002007575,"about_ca_system_score_gemma":0.0002406105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007422373,"about_ca_topic_score_gemma":0.003165684,"domain_scores_codex":[0.9995378,0.0001604265,0.0001241978,0.00003868938,0.0001117352,0.00002717907],"domain_scores_gemma":[0.9979404,0.0008918266,0.0007765369,0.0000557338,0.0002093486,0.0001260406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02869037,0.001418639,0.5287416,0.006567264,0.003278436,0.01538589,0.001178239,0.0003239044,0.05873783,0.0005605887,0.002864734,0.3522525],"study_design_scores_gemma":[0.000681524,0.007502476,0.9549503,0.0006136601,0.002485152,0.01640255,0.0007362208,0.0003159754,0.007867204,0.0003216238,0.008095071,0.00002835335],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9276373,0.05766034,0.0003295176,0.0009263535,0.00015546,0.00008477802,0.0008825635,0.00002597603,0.01229756],"genre_scores_gemma":[0.9830794,0.01433517,0.0005027016,0.0006145476,0.0002377425,0.00002352793,0.0002412773,0.000003877308,0.0009617235],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004071499,"threshold_uncertainty_score":0.01362056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0134263224650046,"score_gpt":0.2981972947770203,"score_spread":0.2847709723120157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}