{"id":"W1998642730","doi":"10.1021/jf990548t","title":"Development and Evaluation of an Immunological Approach for the Identification of Novel Acetyl Coenzyme-A Carboxylase Inhibitors:  Assay Optimization and Pilot Screen Results","year":2000,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Hapten; Monoclonal antibody; Chemistry; Conjugate; Pyruvate carboxylase; Biochemistry; Enzyme; Antibody; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001398811,0.001069631,0.0007452012,0.0004645251,0.0003207316,0.0005527143,0.000735867,0.0005595603,0.0007906902],"category_scores_gemma":[0.000914138,0.0002820599,0.0004209751,0.0003367746,0.0003624831,0.0002231732,0.0003367661,0.0006477782,0.0004582078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004775638,"about_ca_system_score_gemma":0.00039925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001740255,"about_ca_topic_score_gemma":0.002225528,"domain_scores_codex":[0.9988779,0.0003423812,0.0001034547,0.0001378602,0.0004046908,0.000133592],"domain_scores_gemma":[0.9995165,0.00014336,0.00005672085,0.00005821915,0.0001636034,0.00006163934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007942502,0.0002369552,0.0001908064,0.00005470407,0.000009108967,0.00002848732,0.00002104076,0.0001672323,0.9969677,0.00003775371,0.00002330899,0.002183389],"study_design_scores_gemma":[0.00003053662,0.001090499,0.0009391497,0.000002499425,0.00003397499,0.0001229758,0.00001288492,0.0006318223,0.9962816,0.00001058127,0.0008383068,0.000005189347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9392347,0.002563034,0.0529612,0.0002311199,0.00005129294,0.001687265,0.0005074525,0.0001916949,0.002572204],"genre_scores_gemma":[0.9134032,0.003339603,0.07674404,0.0001866251,0.00005110803,0.0008761183,0.001556788,0.00005541554,0.003787129],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001740255,"threshold_uncertainty_score":0.007397711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02529821624032033,"score_gpt":0.2419900336064703,"score_spread":0.2166918173661499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}