{"id":"W1998664238","doi":"10.1016/j.clinbiochem.2006.01.023","title":"Frequency of CYP2C9 polymorphisms affecting warfarin metabolism in a large anticoagulant clinic cohort","year":2006,"lang":"en","type":"article","venue":"Clinical Biochemistry","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto","funders":"","keywords":"CYP2C9; Warfarin; Genotype; Genotyping; Internal medicine; Allele frequency; Allele; Gastroenterology; Genotype frequency; Medicine; Restriction fragment length polymorphism; Cohort; Anticoagulant; Biology; Genetics; Gene; Atrial fibrillation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005750306,0.0004978784,0.0008664878,0.001660419,0.001504318,0.001037618,0.0006802123,0.001056331,0.004307101],"category_scores_gemma":[0.003375743,0.0007968754,0.0005583556,0.001473711,0.0007215195,0.0005301918,0.0004736012,0.00101721,0.0006673759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002910746,"about_ca_system_score_gemma":0.0003427652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005519352,"about_ca_topic_score_gemma":0.003726225,"domain_scores_codex":[0.9989232,0.0003058396,0.00009543925,0.0003849489,0.0001379917,0.0001525182],"domain_scores_gemma":[0.9981736,0.0005829926,0.0003859108,0.0002400704,0.0001705171,0.0004469609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005068639,0.0001592817,0.9942331,0.000005802785,0.00008920673,0.001162064,0.0003010182,0.00004313159,0.002128437,0.00004413978,0.0002200079,0.001107063],"study_design_scores_gemma":[0.00004944404,0.0002282896,0.9955828,0.000002694279,0.00008191133,0.003091371,0.000332437,0.0002695546,0.0001475836,0.00003453959,0.0001682607,0.00001120369],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994413,0.00005679934,0.00006767803,0.00003464754,0.00000470355,0.000004871809,0.0001216356,0.000004825637,0.000263492],"genre_scores_gemma":[0.9994786,0.000031113,0.00006535096,0.00003273236,0.00001394478,0.000007694327,0.0001448258,0.000005949113,0.0002198122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005519352,"threshold_uncertainty_score":0.01440865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08773732555880336,"score_gpt":0.4538236815173983,"score_spread":0.366086355958595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}