{"id":"W1998688570","doi":"10.1016/j.clinthera.2015.03.021","title":"Economic Comparison of an Empirical Versus Diagnostic-Driven Strategy for Treating Invasive Fungal Disease in Immunocompromised Patients","year":2015,"lang":"en","type":"article","venue":"Clinical Therapeutics","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"Pfizer","keywords":"Medicine; Caspofungin; Voriconazole; Incidence (geometry); Aspergillosis; Adverse effect; Neutropenia; Cumulative incidence; Amphotericin B; Internal medicine; Intensive care medicine; Immunology; Antifungal; Chemotherapy; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004554334,0.0001603331,0.0006516739,0.00003948834,0.00003405309,0.00001336489,0.0001454022,0.0001580475,0.00001436659],"category_scores_gemma":[0.001649082,0.0001384098,0.0002075258,0.00006379826,0.0002207513,0.00008421728,0.00003412961,0.0002485297,0.000009140691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001469699,"about_ca_system_score_gemma":0.000628955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001847189,"about_ca_topic_score_gemma":0.0001888354,"domain_scores_codex":[0.9980521,0.0002004605,0.0009844244,0.0003513869,0.0001660948,0.0002454957],"domain_scores_gemma":[0.995689,0.003137601,0.0002349881,0.0004065612,0.0001884826,0.0003434219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0125625,0.002188016,0.9670864,0.00005005333,0.000086065,0.000004833971,0.0002824475,0.0003058593,0.00003205381,0.00003149156,0.00004302241,0.01732724],"study_design_scores_gemma":[0.01573766,0.0051791,0.9617294,0.00007998281,0.0002125316,9.489506e-8,0.00059099,0.01560675,0.0002139282,0.0003036203,0.000191388,0.0001545648],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981822,0.0002452596,0.00007766412,0.0001081626,0.0002794166,0.000843989,0.00006665235,0.00001972681,0.0001768867],"genre_scores_gemma":[0.9986345,0.00006031574,0.0008118096,0.000148283,0.0001456429,0.00002778261,0.0001288759,0.00002205952,0.00002076573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01717268,"threshold_uncertainty_score":0.5644187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2854404408326409,"score_gpt":0.4930723065587755,"score_spread":0.2076318657261347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}