{"id":"W1998699419","doi":"10.1128/aac.00294-13","title":"Potentiation of Azole Antifungals by 2-Adamantanamine","year":2013,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Center for Research Resources; National Institute of Dental and Craniofacial Research; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Harvard University","keywords":"Fluconazole; Lanosterol; Ergosterol; Azole; Candida albicans; Miconazole; Corpus albicans; Microbiology; In vivo; Pharmacology; Amphotericin B; Nystatin; Biofilm; Biology; Chemistry; Antibiotics; Antifungal; Biochemistry; Sterol; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001152253,0.0003941386,0.000420229,0.0002887394,0.0001074504,0.0003112719,0.0002485669,0.0001676791,0.001623247],"category_scores_gemma":[0.0001489335,0.0001070374,0.0003755479,0.0002147227,0.0001360169,0.000192827,0.0002342647,0.0004579535,0.0004136985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001091425,"about_ca_system_score_gemma":0.0001499276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002785287,"about_ca_topic_score_gemma":0.0005050292,"domain_scores_codex":[0.9998733,0.00002649071,0.00001518746,0.00002167642,0.00003794616,0.00002550429],"domain_scores_gemma":[0.9999211,0.00001546207,0.00001859923,0.000008813182,0.00002022535,0.00001576174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003493903,0.0001075625,0.0003581999,0.0002027177,0.00002449276,0.000141601,0.00001689975,0.0002717051,0.9884903,0.00007388158,0.000128838,0.009834235],"study_design_scores_gemma":[0.00007743624,0.002711862,0.00625637,0.00003425948,0.00007828704,0.0005668343,0.00004826171,0.001201038,0.9764097,0.00009532308,0.0125062,0.0000144606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98025,0.01190169,0.002123996,0.0002101558,0.0001272854,0.000103266,0.000628876,0.0001335158,0.004521219],"genre_scores_gemma":[0.9858589,0.007107673,0.003746297,0.0001080304,0.00005411537,0.00005015618,0.001031557,0.00001797054,0.002025364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001623247,"threshold_uncertainty_score":0.005430281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006304477509692223,"score_gpt":0.2357175175366092,"score_spread":0.229413040026917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}