{"id":"W1998703443","doi":"10.1111/liv.12252","title":"Lipopolysaccharide precipitates hepatic encephalopathy and increases blood–brain barrier permeability in mice with acute liver failure","year":2013,"lang":"en","type":"article","venue":"Liver International","topic":"Liver Disease and Transplantation","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Saint-Luc","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Hepatic encephalopathy; Blood–brain barrier; Lipopolysaccharide; Encephalopathy; Internal medicine; Liver function; Liver injury; Immunology; Pathology; Endocrinology; Central nervous system; Cirrhosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004178537,0.001084269,0.0005367361,0.0008591209,0.0002445115,0.0003469258,0.0002845372,0.0005842441,0.001571767],"category_scores_gemma":[0.0002517159,0.0003699153,0.0005285562,0.0002622778,0.0005357736,0.0004306897,0.0003876221,0.001725185,0.0006113001],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004401118,"about_ca_system_score_gemma":0.0003568555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004520458,"about_ca_topic_score_gemma":0.0005984269,"domain_scores_codex":[0.9996777,0.0000685965,0.00003768089,0.00004342407,0.00005682659,0.0001158551],"domain_scores_gemma":[0.9993272,0.00004573686,0.0002774183,0.00005715515,0.0000507226,0.0002417536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00343709,0.001086381,0.001168022,0.0001246752,0.00002720589,0.0003421605,0.00009933893,0.0001910682,0.9908822,0.0001410848,0.0001507308,0.002350135],"study_design_scores_gemma":[0.0007737394,0.0254819,0.03498197,0.00008784568,0.0001051365,0.00145395,0.0003129219,0.002889326,0.9307513,0.0003470913,0.00276405,0.00005066592],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955586,0.001179186,0.001480698,0.0002808799,0.00007863544,0.00007958506,0.0003961569,0.0001670643,0.000779109],"genre_scores_gemma":[0.9937682,0.00107996,0.001938806,0.0001829429,0.00003790395,0.0001941453,0.0005647632,0.00003419357,0.002199037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001571767,"threshold_uncertainty_score":0.005258083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005624427404732413,"score_gpt":0.2199240105365198,"score_spread":0.2142995831317874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}