{"id":"W1998703443","doi":"10.1111/liv.12252","title":"Lipopolysaccharide precipitates hepatic encephalopathy and increases blood–brain barrier permeability in mice with acute liver failure","year":2013,"lang":"en","type":"article","venue":"Liver International","topic":"Liver Disease and Transplantation","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Saint-Luc","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Hepatic encephalopathy; Blood–brain barrier; Lipopolysaccharide; Encephalopathy; Internal medicine; Liver function; Liver injury; Immunology; Pathology; Endocrinology; Central nervous system; Cirrhosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008537414,0.000156965,0.0001684845,0.000137356,0.00004015408,0.00005343638,0.0001013077,0.00005774533,0.001271891],"category_scores_gemma":[0.00003204157,0.0001253746,0.00004392065,0.00006863326,0.0001135205,0.0005436076,0.00003255043,0.0001396597,0.00006560025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004317966,"about_ca_system_score_gemma":0.00007709818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003311273,"about_ca_topic_score_gemma":0.0005751839,"domain_scores_codex":[0.9989448,0.00005470584,0.0001995976,0.0003208669,0.0003120297,0.0001680074],"domain_scores_gemma":[0.999334,0.0001808446,0.00005464574,0.0001163909,0.0001610981,0.0001530701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004510935,0.0004158165,0.9794151,0.0001347517,0.0006888123,0.0004800268,0.003581524,0.000003758396,0.01351849,0.0004144107,0.0001770932,0.0007191286],"study_design_scores_gemma":[0.002438129,0.0002454416,0.9852631,0.0002518352,0.0005944063,0.0003454887,0.0004108793,0.002154456,0.007724152,0.0003241285,0.00004474883,0.0002032263],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979443,0.0002028569,0.00006367989,0.0007660872,0.00004665822,0.0004592342,0.00009644651,0.00003648066,0.0003842896],"genre_scores_gemma":[0.9973754,0.0002266278,0.001081429,0.0006068149,0.00009492315,0.00009951997,0.0001484077,0.00001392904,0.0003528965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00584801,"threshold_uncertainty_score":0.9996411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005624427404732413,"score_gpt":0.2199240105365198,"score_spread":0.2142995831317874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}