{"id":"W1998771362","doi":"10.1016/j.cmet.2010.03.014","title":"Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner","year":2010,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":874,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Air Force Research Laboratory; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Canadian Institutes of Health Research","keywords":"mTORC1; AMPK; Metformin; Cell biology; GTPase; Small GTPase; Biology; Signal transduction; Endocrinology; PI3K/AKT/mTOR pathway; Diabetes mellitus; Phosphorylation; Protein kinase A","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004891357230493326,"score_gpt":0.2170525270742573,"score_spread":0.212161169843764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}