{"id":"W1998793432","doi":"10.1016/j.cyto.2011.11.010","title":"Erythropoietin mimetic compound AGEM400(HES) binds to the same receptor as erythropoietin but displays a different spectrum of activities","year":2011,"lang":"en","type":"article","venue":"Cytokine","topic":"Erythropoietin and Anemia Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Bundesministerium für Bildung und Forschung; Health Sciences Centre Foundation","keywords":"Erythropoietin; Erythropoiesis; Erythropoietin receptor; Haematopoiesis; Hydroxyethyl starch; Receptor; Transfection; Chemistry; Recombinant DNA; Cell biology; Cell culture; Cancer research; Endocrinology; Internal medicine; Biology; Biochemistry; Stem cell; Medicine; Anemia; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002797284,0.0005933754,0.0009784997,0.0002350151,0.0002498953,0.00003763775,0.0003880822,0.0001859331,0.005335154],"category_scores_gemma":[0.0001309001,0.0003747852,0.0003935685,0.0004400696,0.0006887923,0.00007690525,0.0002776256,0.0004546133,0.0007188002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002466839,"about_ca_system_score_gemma":0.0001156443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000911372,"about_ca_topic_score_gemma":0.0001725403,"domain_scores_codex":[0.9970707,0.0001599866,0.0006836994,0.0006668665,0.0006820222,0.0007366859],"domain_scores_gemma":[0.997872,0.000230053,0.0002742757,0.001134045,0.00009165936,0.0003979476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01254456,0.02071121,0.1472611,0.002564411,0.004236862,0.001566464,0.05172334,0.00001974898,0.4769488,0.01221712,0.249081,0.02112537],"study_design_scores_gemma":[0.006794598,0.008267121,0.07731557,0.001278777,0.001048915,0.0006802252,0.01183749,0.00003500478,0.8233079,0.000807341,0.06747817,0.001148914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9672286,0.0004527313,0.0001585338,0.0183379,0.0006689082,0.001135486,0.0001310535,0.000150426,0.01173638],"genre_scores_gemma":[0.9868125,0.000411474,0.001722147,0.0008887583,0.0004915408,0.00011207,0.00009487302,0.0001030911,0.009363603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.346359,"threshold_uncertainty_score":0.9998704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02555044105059446,"score_gpt":0.2603091983984746,"score_spread":0.2347587573478801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}