{"id":"W1998796741","doi":"10.1038/sj.onc.1207226","title":"Expression of activated M-Ras in a murine mammary epithelial cell line induces epithelial–mesenchymal transition and tumorigenesis","year":2004,"lang":"en","type":"article","venue":"Oncogene","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver Hospital and Health Sciences Centre; University of British Columbia","funders":"Cancer Research Institute","keywords":"Biology; Carcinogenesis; Epithelial–mesenchymal transition; Matrigel; Vimentin; Cell culture; Cancer research; Cell growth; Mammary tumor; Mesenchymal stem cell; Molecular biology; Cell biology; Downregulation and upregulation; Angiogenesis; Cancer; Immunology; Immunohistochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003181624,0.0005270173,0.000307055,0.0008388162,0.0003200406,0.00045242,0.0003373444,0.0005191725,0.001649045],"category_scores_gemma":[0.0001949436,0.0003864289,0.0005645461,0.0004365907,0.0002984472,0.0003342244,0.0002809471,0.001095652,0.0008142107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006039476,"about_ca_system_score_gemma":0.0003336657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001231999,"about_ca_topic_score_gemma":0.001902041,"domain_scores_codex":[0.9995288,0.00009858357,0.00006108516,0.00005261808,0.0001058145,0.0001530795],"domain_scores_gemma":[0.9995971,0.0001067931,0.0000810872,0.00009204793,0.00003430751,0.00008868481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001671099,0.00005592273,0.0001191721,0.00001331165,0.000003719178,0.00006868308,0.0000140844,0.00004085554,0.9990416,0.000197319,0.00002128356,0.0002568685],"study_design_scores_gemma":[0.000009416979,0.0001435622,0.0008359776,0.000002309606,0.00000925021,0.0001116701,0.0000215809,0.0004102299,0.9975731,0.00003433241,0.000846953,0.000001689288],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932769,0.001006979,0.002664489,0.0001479002,0.00006044359,0.00005317601,0.0005461324,0.0001453612,0.002098679],"genre_scores_gemma":[0.9932399,0.0005024897,0.00183187,0.00003569884,0.00001582947,0.00004383233,0.0006695889,0.0000318067,0.003628966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001649045,"threshold_uncertainty_score":0.005516648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009136337901732848,"score_gpt":0.2227432798693293,"score_spread":0.2136069419675965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}