{"id":"W1998798768","doi":"10.1038/gt.2013.24","title":"MicroRNA-regulated non-viral vectors with improved tumor specificity in an orthotopic rat model of hepatocellular carcinoma","year":2013,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Hepatocellular carcinoma; microRNA; Biology; Virology; Vector (molecular biology); Viral vector; Cancer research; Gene; Genetics; Recombinant DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006830468,0.0008107105,0.0008059427,0.0008391353,0.0002930212,0.0004264308,0.0005307566,0.0004536581,0.0009753429],"category_scores_gemma":[0.000261899,0.0004005753,0.0005074769,0.0004730824,0.0006383169,0.0006197825,0.0002316217,0.001046099,0.000399627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005310931,"about_ca_system_score_gemma":0.0006680749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001247192,"about_ca_topic_score_gemma":0.001709753,"domain_scores_codex":[0.9994419,0.0001130567,0.00005242704,0.00008215368,0.0001603388,0.0001500208],"domain_scores_gemma":[0.9997328,0.0000482263,0.00007922342,0.0000401052,0.00003188211,0.00006765129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004190555,0.0001631913,0.00004655581,0.00004783722,0.000006981571,0.00006583887,0.00002687722,0.0001379469,0.9971352,0.0003994693,0.00006142585,0.00148967],"study_design_scores_gemma":[0.00003439692,0.0006972993,0.0002656983,0.00000207945,0.0000214454,0.00009907375,0.00001136478,0.0005887903,0.9976735,0.00003021691,0.0005700975,0.000006207305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869748,0.001341541,0.009345148,0.0002392677,0.0001546373,0.0001066946,0.0002676961,0.0002874116,0.001282797],"genre_scores_gemma":[0.9846128,0.001283491,0.008698309,0.00005164561,0.00003767061,0.0001348146,0.0004130863,0.0001126524,0.004655578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001247192,"threshold_uncertainty_score":0.003853381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01300811297320268,"score_gpt":0.212686047960424,"score_spread":0.1996779349872213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}