{"id":"W1998827784","doi":"10.1046/j.1365-2567.2003.01489.x","title":"Tumour necrosis factor‐α (TNF‐α) transgene‐expressing dendritic cells (DCs) undergo augmented cellular maturation and induce more robust T‐cell activation and anti‐tumour immunity than DCs generated in recombinant TNF‐α","year":2003,"lang":"en","type":"article","venue":"Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"Dendritic cell; Tumor necrosis factor alpha; CD86; Biology; Chemokine; Immune system; Cytotoxic T cell; C-C chemokine receptor type 7; T cell; Immunology; CD40; Cell biology; Cancer research; Chemokine receptor; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004619408,0.0005905218,0.0007633301,0.0005167251,0.0006962572,0.0001191114,0.0002951815,0.0008878725,0.0002005468],"category_scores_gemma":[0.0001102096,0.0005825908,0.0001101784,0.0004415473,0.0005227828,0.000526874,0.00009439149,0.001083569,0.00003296529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001663873,"about_ca_system_score_gemma":0.0001861476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007929683,"about_ca_topic_score_gemma":0.0000531952,"domain_scores_codex":[0.9956186,0.001938145,0.0008231752,0.0006840771,0.00007598959,0.0008599451],"domain_scores_gemma":[0.9986142,0.0003733456,0.0003588033,0.0004839501,0.0001302072,0.00003948704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008429865,0.0004164712,0.0007093583,0.00005514076,0.0002027158,0.00001563915,0.002234565,0.00005665606,0.993281,0.00009671673,0.00004855137,0.002040187],"study_design_scores_gemma":[0.004530839,0.0003034068,0.0440621,0.0001611759,0.00005618595,0.0001614013,0.001985844,0.00005283712,0.9469871,0.00009761534,0.001025574,0.0005759323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788008,0.0180759,0.0009661771,0.0002048546,0.0011201,0.0006146743,0.00002583569,0.0001021844,0.00008949153],"genre_scores_gemma":[0.9951313,0.003383286,0.0002137049,0.0001171538,0.00001347591,0.00004893978,0.0002265327,0.00007399743,0.0007915657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04629393,"threshold_uncertainty_score":0.9996626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02035537880297745,"score_gpt":0.2306227314483606,"score_spread":0.2102673526453832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}