{"id":"W1998827784","doi":"10.1046/j.1365-2567.2003.01489.x","title":"Tumour necrosis factor‐α (TNF‐α) transgene‐expressing dendritic cells (DCs) undergo augmented cellular maturation and induce more robust T‐cell activation and anti‐tumour immunity than DCs generated in recombinant TNF‐α","year":2003,"lang":"en","type":"article","venue":"Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"Dendritic cell; Tumor necrosis factor alpha; CD86; Biology; Chemokine; Immune system; Cytotoxic T cell; C-C chemokine receptor type 7; T cell; Immunology; CD40; Cell biology; Cancer research; Chemokine receptor; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001321739,0.0002598416,0.0002636065,0.0001171606,0.00008277794,0.0003380376,0.00007826918,0.0001925535,0.000941472],"category_scores_gemma":[0.0001109308,0.0001081538,0.0001544698,0.0001427288,0.0001808476,0.000188662,0.0001130166,0.000785218,0.0004194838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001956227,"about_ca_system_score_gemma":0.0001357813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001981396,"about_ca_topic_score_gemma":0.0001846155,"domain_scores_codex":[0.9998529,0.00002364404,0.00001740585,0.00003466062,0.00003607828,0.00003521064],"domain_scores_gemma":[0.9998847,0.00001914485,0.00003674232,0.0000147249,0.00001882002,0.00002586206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007766233,0.00001859911,0.00009669779,0.00001767824,0.000001928523,0.00001294786,0.000007511346,0.00002121411,0.99919,0.00002186562,0.00001003113,0.0005238909],"study_design_scores_gemma":[0.0000150044,0.000298848,0.001468631,0.000002924875,0.00001074581,0.0001906908,0.00001239898,0.0001936138,0.9959507,0.00001917223,0.00183546,0.000001782849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926835,0.001446415,0.004375413,0.0000690719,0.00004940604,0.00003466409,0.0002217039,0.00006698408,0.001052704],"genre_scores_gemma":[0.9941969,0.001068093,0.002495547,0.00003715835,0.0000157837,0.00002065265,0.0003953608,0.00001314955,0.001757333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000941472,"threshold_uncertainty_score":0.003149569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02035537880297745,"score_gpt":0.2306227314483606,"score_spread":0.2102673526453832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}