{"id":"W1998843697","doi":"10.1246/cl.141045","title":"Synthesis and G-Quadruplex-binding Properties of Cationic Platinum(II) Terpyridine Complexes Containing σ-Alkynyl Auxiliaries","year":2014,"lang":"en","type":"article","venue":"Chemistry Letters","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Science North","funders":"","keywords":"Chemistry; Terpyridine; Cationic polymerization; G-quadruplex; Cisplatin; Duplex (building); DNA; Stereochemistry; Platinum; Combinatorial chemistry; Selectivity; Cytotoxicity; Polymer chemistry; Metal; Organic chemistry; In vitro; Biochemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001491723,0.0002151961,0.0002500776,0.00001589692,0.0001793783,0.00003078082,0.0002119232,0.0001317074,0.00003667858],"category_scores_gemma":[0.0002850012,0.0002075979,0.00007089105,0.00004796324,0.0003682876,0.000008248361,0.0001717191,0.0001003545,0.00000170593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001774177,"about_ca_system_score_gemma":0.00003030485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001194474,"about_ca_topic_score_gemma":0.000001440118,"domain_scores_codex":[0.9989641,0.00001891984,0.0002767227,0.0003557728,0.000132267,0.0002522181],"domain_scores_gemma":[0.9993401,0.00003004194,0.0001626496,0.0003393975,0.00004843243,0.00007941622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006116286,0.00002209151,0.002112076,0.0002455126,0.00005970879,7.846745e-7,0.0001689755,0.00001367922,0.9962062,0.00001088018,0.0006432961,0.0004556721],"study_design_scores_gemma":[0.0003173261,0.00002131721,0.0001749929,0.0001044494,0.0000350939,0.00002377866,0.0002324166,0.000102441,0.9953927,0.000008132216,0.003341582,0.0002457533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977927,0.0002434756,0.0001306931,0.0006642748,0.00003303128,0.00006294236,0.00001713548,0.00002453593,0.001031196],"genre_scores_gemma":[0.998902,0.00002814332,0.000344233,0.0001955432,0.0001941683,0.00002374533,0.0000662645,0.0000277285,0.0002181958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002698286,"threshold_uncertainty_score":0.8465599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009272515955028536,"score_gpt":0.1998045534742299,"score_spread":0.1905320375192013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}