{"id":"W1998975283","doi":"10.1111/j.1432-1033.2004.04360.x","title":"Alternative substrates for wild‐type and L109A <i>E. coli</i> CTP synthases","year":2004,"lang":"en","type":"article","venue":"European Journal of Biochemistry","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of California, Davis; Nova Scotia Health Research Foundation","keywords":"ATP synthase; Glutamine amidotransferase; Glutamine; Chemistry; Biochemistry; Enzyme; Guanosine; ATP hydrolysis; Uridine; Cytidine; Stereochemistry; Amino acid; RNA; ATPase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003773702,0.0004283252,0.0005230505,0.0001727579,0.000162514,0.0008149062,0.0005244106,0.0008501335,0.0007062528],"category_scores_gemma":[0.0008123364,0.0002299158,0.0002843864,0.0003541148,0.0003232555,0.00048242,0.0004506572,0.0009039522,0.000402953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006503806,"about_ca_system_score_gemma":0.0002395681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005042184,"about_ca_topic_score_gemma":0.0006642507,"domain_scores_codex":[0.9993648,0.000141391,0.0001119637,0.0001243661,0.000184736,0.00007270546],"domain_scores_gemma":[0.9993444,0.0001664123,0.000138115,0.0001008304,0.00009597364,0.0001542457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000187655,0.00003326293,0.0003023241,0.00004568539,0.000004560023,0.00008525003,0.00002131121,0.00008875436,0.9984626,0.0001899034,0.00003508226,0.0005436389],"study_design_scores_gemma":[0.00002368399,0.0001953443,0.001933777,0.00000790164,0.000009073889,0.0004141595,0.00005608692,0.001074172,0.9946715,0.00007923543,0.001520561,0.00001444795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951841,0.0006386277,0.002772258,0.0001137106,0.00004308491,0.00002583196,0.0005567687,0.00006052605,0.0006050126],"genre_scores_gemma":[0.9899199,0.0003268239,0.006423064,0.00007738252,0.00001034248,0.00005288884,0.002085762,0.00006206633,0.001041827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008501335,"threshold_uncertainty_score":0.00471884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01486421904106188,"score_gpt":0.2652405002347655,"score_spread":0.2503762811937036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}