{"id":"W1998992488","doi":"10.1371/journal.pone.0120228","title":"High-Dose Intravenous Vitamin C Combined with Cytotoxic Chemotherapy in Patients with Advanced Cancer: A Phase I-II Clinical Trial","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Vitamin C and Antioxidants Research","field":"Nursing","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; Jewish General Hospital","funders":"","keywords":"Medicine; Tolerability; Chemotherapy; Adverse effect; Cancer; Internal medicine; Pharmacokinetics; Oncology; Clinical trial; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004350329,0.000255492,0.0006911556,0.0001511671,0.0001031998,0.00004394647,0.0002584574,0.0001306973,0.00005881665],"category_scores_gemma":[0.0001609861,0.0001907912,0.00004371701,0.0004598575,0.0001874293,0.0002200732,0.00004447682,0.0004682452,0.00002113517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002020192,"about_ca_system_score_gemma":0.0001877782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001337734,"about_ca_topic_score_gemma":0.0001946586,"domain_scores_codex":[0.9973232,0.0002074032,0.0005018866,0.0004964286,0.0009124198,0.0005586458],"domain_scores_gemma":[0.998745,0.0001114854,0.0001821079,0.0004009962,0.0002629538,0.0002974598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7823137,0.08956815,0.04742981,0.0001382388,0.0003841388,0.00007034529,0.001100774,0.00001856291,0.00358543,0.00001388638,0.0002469163,0.07513008],"study_design_scores_gemma":[0.8041535,0.1353245,0.03828042,0.001017967,0.0001365049,9.699947e-7,0.0001292012,0.0003570246,0.01983803,0.00006892605,0.00009675959,0.0005961943],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965293,0.00003936104,0.00001288451,0.0008824592,0.0001657113,0.002190861,0.00003466568,0.00008098919,0.00006379645],"genre_scores_gemma":[0.9972787,0.00005635467,0.001693215,0.0002384298,0.0002385297,0.0001703855,0.00004464952,0.00007202179,0.0002076531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07453388,"threshold_uncertainty_score":0.7780239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06174272266225636,"score_gpt":0.3393337685554415,"score_spread":0.2775910458931852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}