{"id":"W1999003094","doi":"10.3171/jns.2001.94.2.0281","title":"Augmentation of endothelial function by endothelin antagonism in human saphenous vein conduits","year":2001,"lang":"en","type":"article","venue":"Journal of neurosurgery","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Calgary","keywords":"Bosentan; Medicine; Vasoconstriction; Endothelin receptor; Internal medicine; Endothelin 1; Endothelin receptor antagonist; Cardiology; Antagonist; Endothelial dysfunction; Endothelium; Sodium nitroprusside; Vasodilation; Anesthesia; Receptor; Nitric oxide","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003826211,0.0002506385,0.0002941579,0.0001327893,0.0001037363,0.0003072963,0.0001548351,0.0001355651,0.00124089],"category_scores_gemma":[0.000465789,0.00008165003,0.0001807554,0.0001300665,0.0002240294,0.0001599648,0.0001262181,0.0003801138,0.0001982107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001486839,"about_ca_system_score_gemma":0.000138732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003649928,"about_ca_topic_score_gemma":0.0004287382,"domain_scores_codex":[0.9998241,0.00006941739,0.00001350013,0.00002060194,0.0000373023,0.00003507226],"domain_scores_gemma":[0.9998345,0.00005811861,0.00003576574,0.0000156298,0.00001836809,0.00003756315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004425865,0.000535748,0.002342272,0.0001782136,0.00003829689,0.0003320692,0.00009072386,0.0002391477,0.9760859,0.0001271932,0.0002202422,0.01538445],"study_design_scores_gemma":[0.00134641,0.05167181,0.0794659,0.00007112957,0.0003252094,0.002984203,0.0001672764,0.004883317,0.851753,0.0001192174,0.007187512,0.00002493018],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971792,0.001602962,0.0005087305,0.00003988965,0.0000248432,0.00001964916,0.00003912117,0.00001458609,0.0005710553],"genre_scores_gemma":[0.9976584,0.0008932926,0.0007303184,0.00003969167,0.00003328695,0.00002730728,0.000182682,0.00000375931,0.0004312445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00124089,"threshold_uncertainty_score":0.004151165,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02061854280334352,"score_gpt":0.2807204796441243,"score_spread":0.2601019368407808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}