{"id":"W1999015709","doi":"10.1371/journal.pone.0118335","title":"Mechanosensitive Gating of Kv Channels","year":2015,"lang":"en","type":"review","venue":"PLoS ONE","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Ottawa Hospital Research Institute","keywords":"Mechanosensitive channels; Gating; Biophysics; Lipid bilayer; Ion channel; Membrane potential; Chemistry; Bilayer; Physics; Sodium channel; Membrane; Biology; Biochemistry; Sodium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001698024,0.0002547824,0.0001507194,0.0001762329,0.0001379211,0.0004908466,0.0003700351,0.0003290598,0.001114267],"category_scores_gemma":[0.0004915316,0.0001606245,0.0003581322,0.000131756,0.0003417647,0.000921676,0.0004840492,0.0005591556,0.0002784591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004755272,"about_ca_system_score_gemma":0.0001254277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003076597,"about_ca_topic_score_gemma":0.0002848972,"domain_scores_codex":[0.9998467,0.00001686064,0.00000919932,0.00004031739,0.00004920382,0.00003771767],"domain_scores_gemma":[0.9998668,0.00003305427,0.00003671533,0.00001991166,0.00002274742,0.00002068855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009763757,0.00002012467,0.002306824,0.0001192565,0.00001293217,0.0002022234,0.00007112951,0.002203874,0.9796133,0.003844384,0.0004395141,0.01106886],"study_design_scores_gemma":[0.00005348425,0.0004283642,0.04554605,0.0000582229,0.00003014633,0.001734409,0.0002242368,0.05727491,0.8702192,0.0109611,0.01336592,0.0001038645],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9652704,0.001899807,0.02437416,0.0006416683,0.0001110149,0.00003926062,0.000342605,0.0004722189,0.006848937],"genre_scores_gemma":[0.9969222,0.0005884687,0.001501012,0.0001967266,0.00001477336,0.00001441293,0.0001349381,0.00001610635,0.0006113414],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001114267,"threshold_uncertainty_score":0.003727615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1244357261550993,"score_gpt":0.3040103765333713,"score_spread":0.179574650378272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}